Chemical Name: 8-(1-Naphthalenylmethyl)-4-oxo-1-phenyl-1,3,8-triazaspiro[4.5]decane-3-acetic acid, methyl ester
Biological ActivityPotent non-peptide agonist for the NOP receptor (EC50 = 305 nM, Ki = 7.3 nM); ~ 12-fold selective over other receptors. Centrally active following systemic administration in vivo.
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For batch specific data refer to the Certificate of Analysis.
Tocris products are intended for laboratory research use only, unless stated otherwise.
(8-Naphthalen-1-ylmethyl-4-oxo-1-phenyl-1,3,8-triaza-spiro[4.5]-dec-3-yl)-acetic acid methyl ester (NNC 63-0532) is a novel potent nociceptin receptor agonist.
Thomsen and Hohlweg
Citation for NNC 63-0532
The citations listed below are publications that use Tocris products. Selected citations for NNC 63-0532 include:
1 Citation: Showing 1 - 1
NOP receptor mediates anti-analgesia induced by agonist-antagonist opioids.
Authors: Gear Et al.
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VersaClone cDNA Plasmids
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