Non-Human Primate uPAR Cartridge
R&D Systems | Catalog # SPCKB-NP-011345
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Key Product Details
Assay Length
Sample Type & Volume Required Per Well*
Sensitivity
Assay Range
Non-Human Primate uPAR Cartridge Summary
*The Sample Volume represented is based on the amount of sample incorporated into the reaction after taking into account the assay's minimum required dilution for a given matrix. Serial dilution may be necessary to achieve some of the final sample volumes represented.
Compatible Instruments
Ella Automated Immunoassay System
Product Specifications
Assay Type
Format
Species
Specificity
Cross-reactivity
Interference
Precision
Intra-Assay Precision (Precision within an assay) Each control was tested 16 times in one assay.
Inter-Assay Precision (Precision between assays) Replicates of each control were tested in multiple assays performed by at least three technicians using two lots of reagents.
Cell Culture Supernates, EDTA Plasma, Heparin Plasma, Serum
| Intra-Assay Precision | Inter-Assay Precision | |||
|---|---|---|---|---|
| Sample | 1 | 2 | 1 | 2 |
| n | 16 | 16 | 49 | 50 |
| Mean (pg/mL) | 120 | 6099 | 110 | 5748 |
| Standard Deviation | 6.80 | 261 | 8.51 | 558 |
| CV% | 5.7 | 4.3 | 7.7 | 9.7 |
Recovery for Non-Human Primate uPAR Cartridge
Recovery was not necessary as uPAR shows 5 points of natural linearity.
Linearity
Samples containing and/or spiked with high concentrations of uPAR were serially diluted with Sample Diluent to produce samples within the dynamic range of the assay.
Scientific Data Images for Non-Human Primate uPAR Cartridge
Non-Human Primate uPAR Ella Assay Standard Curve
Preparation and Storage
Shipping
Stability & Storage
Background: uPAR
The urokinase-type Plasminogen Activator Receptor (uPAR) is a GPI-anchored protein that binds to both the inactive and active forms of uPA. This interaction serves to localize and enhance the proteolytic activity of uPA, leading to increased conversion of Plasminogen to Plasmin. uPA also triggers uPAR-mediated signal transduction, activation of protein tyrosine kinases, gene expression, cell adhesion, and chemotaxis. uPAR can additionally regulate cell adhesion by direct binding to Vitronectin and preventing Integrins from binding to their ligands.
Long Name
Alternate Names
Gene Symbol
Additional uPAR Products
Product Documents for Non-Human Primate uPAR Cartridge
Certificate of Analysis
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Product Specific Notices for Non-Human Primate uPAR Cartridge
For research use only
Citations for Non-Human Primate uPAR Cartridge
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