Ella Automated Immunoassay System
What Is Ella?
Ella is a next-generation automated benchtop immunoassay platform designed to deliver accurate, reproducible data with no manual steps. Utilizing a unique microfluidic design, the Ella platform’s Simple Plex Assays are fully validated, highly sensitive and can assay up to 8 analytes simultaneously in less than 90 minutes.
How Can Ella Work for You?
Achieve fast, accurate biomarker results with Ella. The automated immunoassay Ella platform brings a higher level of precision and minimal training, increasing your productivity in the lab. Running an assay requires simply adding diluted samples and wash buffer to the cartridge before placing the cartridge inside the Ella instrument.
Product Highlights
| Automated Workflow | Ella is a fully automated cartridge-based system that enables you to measure biomarkers in multiple sample types. Ella, together with microfluidic technology (Simple Plex Cartridges), allow for single analyte, multiple analytes in parallel (multi-analyte), and multiplexed measurements. You can also configure Simple Plex cartridges to be unique to your own research and reagents. |
| Fast Results | • Execute an automated immunoassay protocol with fully analyzed results in less than 90 mins • Built-in standard curve, decreasing time to results • Extract and save fluorescence and concentration information for application-specific analysis |
| Use less of your limited samples | Simple Plex can achieve 4+ logs of quantitative range which allows detection of a wide range of analyte concentrations. Minimize the need for multiple sample dilutions and reduce the sample volume required. Three data replicates are measured in an independent microfluidic channel, so there's no cross-reactivity, providing improved sensitivity and the ability to detect—all with as little as 25 µL per sample. |
How Can the Ella Automated Immunoassay System Help You?
Highly Reproducible
When it's time to develop and transfer your immunoassay to other labs, users, sites or a contract research organization, Ella makes it easy. Because Simple Plex assays are precisely controlled in the cartridge, pipetting errors are limited. You'll get the same reproducible answers across multiple users and multiple sites. Simply put, you'll get consistent answers anywhere, by anyone on any Ella.
Sensitivity
Detection down to the picogram level, and now femtogram level with Simple Plex Ultra-Sensitivity Assays. Ella uses a fluorescent detection system to deliver excellent low-end sensitivity to detect low expressing proteins and provide a broad dynamic range.
Broad Range of Validated Targets
- Cell and Gene Therapy
- Bioprocessing
- Neurology
- Cancer Research
- Immunology
Flexibility
Large assay menu with over 350 validated assays across 4 species: Human, Mouse, Rat, and Non-human primate. Look for an analyte not available, request a custom assays or use the open cartridge to configure the Simple Plex cartridges to be unique to your own research and reagents.
CE-IVDR Class A Instrument
Ella CE-IVD is the CE-IVD marked version of the trusted Ella Immunoassay System now self certified as Class A IVDR instrument for use in the EU. Built on the same proven technology as the RUO Ella system, Ella CE-IVD empowers clinical laboratories and diagnostic developers to confidently advance their in-house test development and clinical trial workflows in accordance with IVDR.
Learn more about Ella CE-IVD
Instrument Specifications
| Description | Single Plex Specification | Multianalyte Specification | Multiplex Specification | Customizable Specification | Ultra-Sensitive Assays |
| Sample Volume Required | 2.5-25 µL | 2.5-25 µL | 2.5-25 µL | 2.5-25 µL | ≤40 µL |
| Dynamic range | 3-4 logs | ||||
| Sensitivity | <1pg/mL (assay dependent) | fg/ml | |||
| Assay Runtime | 75 Minutes | 80 Minutes | 155 min | ||
| Samples per run | Up to 72 | Up to 32 | Up to 32 | Up to 48 | Up to 32 |
| Number of analytes | 1 | Up to 4 | Up to 8 | 1 | Up to 4 |
| Results per run | Up to 72 | Up to 128 | Up to 256 | Up to 48 | Up to 128 |
| Replicates per result | Triplicate | Triplicate | Duplicate | Triplicate | Triplicate |
| Ella Weight | 16 kg (35.3 lbs) | ||||
| Ella Dimensions (closed) | 37 cm W x 54 cm D x 26 cm H | ||||
| Ella Power | 100-240 V(AC), 300 VA, 45/65 Hz, Class I Installation Category (Over Voltage) II | ||||
| Ella Operating temperature | 15 to 30 °C (59° to 86°F) | ||||
| Ella Operating humidity | 15-80% relative, non-condensing | ||||
Dr. Zhong Youjia, Assistant Professor, Department of Paediatrics, Yong Loo Lin School of Medicine, National University of Singapore
"With Ella, we can worry less about manpower and time constraints. It’s convenient, quick, and automated—perfect for pediatric studies with limited sample volume."
Samira Lakhal-Littleton, BSc DPhil, Associate Professor of Cell Physiology, University of Oxford
"Ella’s sensitive and tractable workflow is enabling us to tackle large datasets not previously possible with standard ELISA kits. It has enabled us to more quickly and efficiently discover novel connections between hepcidin and inflammation in the context of chronic disease."
Andrew Nixon Ph.D., M.B.A.,, Associate Professor, Medicine & Director, Duke University
"Ella allows for reproducible sample data with minimal sample input. The lower volume usage allows for the expansion of research into novel areas of angiogenesis and inflammation as they pertain to many forms of cancer."
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