NoxA1ds

Catalog # Availability Size / Price Qty
5848/1
Cat.No. 5848 - NoxA1ds | Glu-Pro-Val-Asp-Ala-Leu-Gly-Lys-Ala-Lys-Val-NH2 | CAS No. 1435893-78-9
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Description: Potent and selective NADPH oxidase 1 (NOX1) inhibitor
Product Details
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Biological Activity

Potent and selective NADPH oxidase 1 (NOX1) inhibitor (IC50 = 20 nM). Exhibits selectivity for NOX1 over NOX2, NOX4, NOX5 and xanthine oxidase. Inhibits NOX1-derived O2- production in HT-29 human colon cancer cells. Attenuates VEGF-induced human pulmonary artery endothelial cell migration under hypoxic conditions in vitro. Cell permeable.

Technical Data

M.Wt:
1125.33
Formula:
C50H88N14O15
Sequence:
EPVDALGKAKV

(Modifications: Val-11 = C-terminal amide)

Solubility:
Soluble to 2 mg/ml in water
Storage:
Store at -20°C
CAS No:
1435893-78-9

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis. All Tocris products are intended for laboratory research use only.

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