NoxA1ds

   
Product Datasheet
Catalog Number:5848
Chemical Name:
Product Details
Reviews
Biological Activity
Potent and selective NADPH oxidase 1 (NOX1) inhibitor (IC50 = 20 nM). Exhibits selectivity for NOX1 over NOX2, NOX4, NOX5 and xanthine oxidase. Inhibits NOX1-derived O2- production in HT-29 human colon cancer cells. Attenuates VEGF-induced human pulmonary artery endothelial cell migration under hypoxic conditions in vitro. Cell permeable.
Technical Data
  • M.Wt:
    1125.33
  • Formula:
    C50H88N14O15
  • Sequence:
    EPVDALGKAKV

    (Modifications: Val-11 = C-terminal amide)

  • Solubility:
    Soluble to 2 mg/ml in water
  • Storage:
    Store at -20°C
  • CAS No:
    1435893-78-9
The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis. All Tocris products are intended for laboratory research use only.
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