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NoxA1ds

Catalog #: 5848 Datasheet / COA / SDS

Discontinued Product

5848 has been discontinued.
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NoxA1ds
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Description: Potent and selective NADPH oxidase 1 (NOX1) inhibitor
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Biological Activity

NoxA1ds is a potent and selective NADPH oxidase 1 (NOX1) inhibitor (IC50 = 20 nM). Exhibits selectivity for NOX1 over NOX2, NOX4, NOX5 and xanthine oxidase. Inhibits NOX1-derived O2- production in HT-29 human colon cancer cells. Attenuates VEGF-induced human pulmonary artery endothelial cell migration under hypoxic conditions in vitro. Cell permeable.

Technical Data

M.Wt:
1125.33
Formula:
C50H88N14O15
Sequence:
EPVDALGKAKV

(Modifications: Val-11 = C-terminal amide)

Solubility:
Soluble to 2 mg/ml in water
Storage:
Store at -20°C
CAS No:
1435893-78-9

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
Tocris products are intended for laboratory research use only, unless stated otherwise.

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