Catalog Number: 3512
Alternate Names: NPE-caged-sulfate
Chemical Name: 1-(2-Nitrophenyl)ethyl sulfate sodium salt
Biological Activity
1-(2-nitrophenyl)ethyl caged proton that releases a proton and a sulfate ion upon photolysis. Generates rapid acidifications down to pH 2 (pH jumps).
Technical Data
  • M.Wt:
    269.21
  • Formula:
    C8H8NNaO6S
  • Solubility:
    Soluble to 100 mM in water and to 100 mM in DMSO
  • Purity:
    >98%
  • Storage:
    Store at -20°C
  • CAS No:
    1186195-63-0
The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis. All Tocris products are intended for laboratory research use only.
Background References
  1. Characterization of a new caged proton capable of inducing large pH jumps.
    Barth and Corrie
    Biophys.J., 2002;83:2864
  2. Kinetics of proton release after flash photolysis of 1-(2-Nitrophenyl)ethyl sulfate (caged sulfate) in aqueous solution.
    Abbruzzetti et al.
    J.Am.Chem.Soc., 2005;127:9865
  3. Time-resolved infrared spectroscopy of pH-induced aggregation of the Alzheimer Aβ1-28 peptide.
    Peralvarez-Marin et al.
    J.Mol.Biol., 2008;379:589

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