Selective inhibitor of apoptosis signal-regulating kinase 1 (ASK1, MAP3K5) (IC50
= 3 μ
= 500 nM).
Soluble to 10 mM in DMSO
Store at +4°C
The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
All Tocris products are intended for laboratory research use only.
Synthesis and cytotoxic activity of 7-oxo-7H-dibenz[f,ij]isoquinoline and 7-oxo-7H-benzo[e]perimidine derivatives.
Bu et al.
Identification of 3H-naphtho[1,2,3-de]quinoline-2,7-diones as inhibitors of apoptosis signal-regulating kinase 1 (ASK1).
Volynets et al.
The citations listed below are publications that use Tocris products. Selected citations for NQDI 1 include:
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