NS 3623

Catalog # Availability Size / Price Qty
4462/10
4462/50
NS 3623 | CAS No. 343630-41-1 | Voltage-gated Potassium Channel Activators
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Description: KV11.1 (hERG) and KV4.3 channel activator; antiarrhythmic

Chemical Name: N-[4-Bromo-2-(1H-tetrazol-5-yl-phenyl]-N'-[3-(trifluoromethyl)phenyl]-urea

Purity: ≥99%

Product Details
Reviews (1)

Biological Activity

KV11.1 (hERG) and KV4.3 channel activator. Activates the IKr and Ito currents and displays antiarrhythmic activity. May also act as a partial blocker of KV11.1 channels. Displays selectivity over the key cardiac potassium channels, KV7.1 (KCNQ1) and KV1.5. Suitable for both in vitro and in vivo use.

Technical Data

M.Wt:
427.18
Formula:
C15H10BrF3N6O
Solubility:
Soluble to 100 mM in DMSO
Purity:
≥99%
Storage:
Store at +4°C
CAS No:
343630-41-1

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
Tocris products are intended for laboratory research use only, unless stated otherwise.

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Product performs well as a channel opener in experimental conditions
By Sadequl Islam on 10/12/2018
Application: Species: Human

Product worked amazing on experimental conditions. Shows channel opening properties and must be dissolved in Tween 20–propylene glycol mixture.NS3623 affects the voltage-dependent potassium channel opening.


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