Chemical Name: 3-(3-Bromo-2-thienyl)-8-methyl-8-azabicyclo[3.2.1]oct-2-ene fumarate
Biological ActivityNS 3861 is a α3β2 full agonist (EC50 = 1.6 μM). Also α3β4 partial agonist (EC50 = 1 μM). Exhibits minimal activity at α4β2 and α4β4. Displays high affinity for α3β4, α4β4, α3β2 and α4β2 (Ki values are 0.62, 7.8, 25 and 55 nM respectively).
The technical data provided above is for guidance only.
For batch specific data refer to the Certificate of Analysis.
Tocris products are intended for laboratory research use only, unless stated otherwise.
Complete Your Research
Complete Your Experiment
Molecular determinants of subtype-selective efficacies of cytisine and the novel compound NS3861 at heteromeric nicotinic acetylcholine receptors.
Harpsøe et al.
No product specific FAQs exist for this product, however you mayView all Small Molecule FAQs
VersaClone cDNA Plasmids
Reviews for NS 3861
There are currently no reviews for this product. Be the first to review NS 3861 and earn rewards!
Have you used NS 3861?
Submit a review and receive an Amazon gift card.
$25/€18/£15/$25CAN/¥75 Yuan/¥1250 Yen for a review with an image
$10/€7/£6/$10 CAD/¥70 Yuan/¥1110 Yen for a review without an image