Chemical Name: E-4,4'-(1,2-Diethyl-1,2-ethenediyl)bis[2-[(diethylamino)methyl]phenol
Biological ActivitySelective inhibitor of JAK2 (IC50 = 60 nM). Displays no effect on Src and TYK2 tyrosine kinase activity at a concentration of 25 μM.
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Tocris products are intended for laboratory research use only, unless stated otherwise.
Identification of a novel inhibitor of JAK2 tyrosine kinase by structure-based virtual screening.
Kiss et al.
Citation for NSC 33994
The citations listed below are publications that use Tocris products. Selected citations for NSC 33994 include:
1 Citation: Showing 1 - 1
Crosstalk between bone marrow-derived myofibroblasts and gastric cancer cells regulates cancer stemness and promotes tumorigenesis.
Authors: Zhu Et al.
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