NSC 33994

Catalog # Availability Size / Price Qty
4338/10
4338/50
NSC 33994 | CAS No. 82058-16-0 | JAK Kinase Inhibitors
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Description: JAK2 inhibitor

Chemical Name: E-4,4'-(1,2-Diethyl-1,2-ethenediyl)bis[2-[(diethylamino)methyl]phenol

Purity: ≥98%

Product Details
Citations (1)
Reviews

Biological Activity

Selective inhibitor of JAK2 (IC50 = 60 nM). Displays no effect on Src and TYK2 tyrosine kinase activity at a concentration of 25 μM.

Technical Data

M.Wt:
438.65
Formula:
C28H42N2O2
Solubility:
Soluble to 5 mM in DMSO with gentle warming and to 10 mM in ethanol with gentle warming
Purity:
≥98%
Storage:
Store at -20°C
CAS No:
82058-16-0

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
Tocris products are intended for laboratory research use only, unless stated otherwise.

Background References

  1. Identification of a novel inhibitor of JAK2 tyrosine kinase by structure-based virtual screening.
    Kiss et al.
    Bioorg.Med.Chem.Lett., 2009;19:3598

Product Datasheets

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Citation for NSC 33994

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