Catalog Number: 4338
Chemical Name: E-4,4'-(1,2-Diethyl-1,2-ethenediyl)bis[2-[(diethylamino)methyl]phenol
Biological Activity
Selective inhibitor of JAK2 (IC50 = 60 nM). Displays no effect on Src and TYK2 tyrosine kinase activity at a concentration of 25 μM.
Technical Data
  • M.Wt:
    438.65
  • Formula:
    C28H42N2O2
  • Solubility:
    Soluble to 5 mM in DMSO with gentle warming and to 10 mM in ethanol with gentle warming
  • Purity:
    >98%
  • Storage:
    Store at -20°C
  • CAS No:
    82058-16-0
The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis. All Tocris products are intended for laboratory research use only.
Background References
  1. Identification of a novel inhibitor of JAK2 tyrosine kinase by structure-based virtual screening.
    Kiss et al.
    Bioorg.Med.Chem.Lett., 2009;19:3598

Have you used NSC 33994?

Submit a review and receive a $25US/€18/£15/$25CAN amazon gift card if you include an image - $10US/€7/£6/$10CAN Amazon card for reviews without an image. Limited to verified customers in USA, Canada and Europe.

Tocris Bioscience is the leading supplier of novel and exclusive tools for life science research with over 30 years' experience in the industry. Tocris is a Bio-Techne brand.

Order Details

Note:

Contact Information

Calculators

Molarity Calculator

Calculate the mass, volume, or concentration required for a solution.
=
x
x
g/mol

*When preparing stock solutions always use the batch-specific molecular weight of the product found on the vial label and SDS / CoA (available online).

R&D Systems Guarantee

Feedback

Customer Information