Chemical Name: 3,4-Dichloro-N-(1-methylbutyl)benzamide
Biological Activity Membrane type-1 matrix metalloproteinase (MT1-MMP) inhibitor (IC50 > 100 μmol/L). Directly interacts with the hemopexin domain (PEX) of MT1-MMP, affecting homodimerization and repressing its pro-tumorigenic activity in vivo. Displays no effect on the catalytic activity of MT1-MMP or MMP-2.
Soluble to 100 mM in DMSO and to 100 mM in ethanol
Store at RT
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