NSC 632839 hydrochloride

Catalog # Availability Size / Price Qty
2647/10
2647/50
NSC 632839 hydrochloride | CAS No. 157654-67-6 | Deubiquitinating Enzyme Inhibitors
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Description: Inhibitor of ubiquitin isopeptidase activity
Alternative Names: F6

Chemical Name: 3,5-Bis[(4-methylphenyl)methylene]-4-piperidone hydrochloride

Purity: ≥99%

Product Details
Citations (2)
Reviews (1)

Biological Activity

Inhibitor of ubiquitin isopeptidase activity that displays no effect on the proteolytic activity of the proteasome. Induces apoptosis via a Bcl-2-dependent and apoptosome-independent pathway of caspase activation (IC50 values are 15.65 and 16.23 μM in E1A and E1A/C9CN cells respectively).

Technical Data

M.Wt:
339.86
Formula:
C21H21NO.HCl
Solubility:
Soluble to 25 mM in DMSO
Purity:
≥99%
Storage:
Store at +4°C
CAS No:
157654-67-6

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
Tocris products are intended for laboratory research use only, unless stated otherwise.

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Citations for NSC 632839 hydrochloride

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42 perturbagens used the zebrafish DASPEI screen
By Anonymous on 12/17/2019
Application: Species: Other

Zebrafish larvae were placed into 48-well plates and used the DASPEI screen by 42 perturbagens drugs, including this compound

PMID: 30532693

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