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NSC 668036

Catalog #: 5813 Datasheet / COA / SDS
Catalog # Availability Size / Price Qty
5813/10
5813/50
NSC 668036 | CAS No. 144678-63-7 | Other Wnt Signaling Inhibitors
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Description: Wnt signaling inhibitor; binds the PDZ domain of the Dishevelled (Dvl) protein

Chemical Name: N-[(1,1-dimethylethoxy)carbonyl]-L-alanyl-(2S)-2-hydroxy-3-methylbutanoyl-L-alanine-(1S)-1-carboxy-2-methylpropyl ester

Purity: ≥98%

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Biological Activity

NSC 668036 is a Wnt signaling inhibitor. Binds the PDZ domain of the Dishevelled (Dvl) protein. Inhibits proliferation, migration and TGF-β-induced differentiation of fibroblasts in vitro. Reduces severity of pulmonary fibrosis in a mouse model.

Technical Data

M.Wt:
460.52
Formula:
C21H36N2O9
Solubility:
Soluble to 100 mM in DMSO and to 100 mM in ethanol
Purity:
≥98%
Storage:
Store at -20°C
CAS No:
144678-63-7

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
Tocris products are intended for laboratory research use only, unless stated otherwise.

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