NTR 368
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Description: p75NTR fragment; induces apoptosis
Alternative Names: Neurotrophin receptor (368-381) amide
Biological Activity
Peptide fragment corresponding to residues 368-381 of the human p75 neurotrophin receptor (p75NTR). Forms a helical structure in the presence of micellar lipid. Induces apoptosis in human neuroblastoma cells in vitro.Technical Data
M.Wt:
1565.87
Formula:
C69H124N22O19
Sequence:
ATLDALLAALRRIQ-amide
(Modifications: Ala-1 = N-terminal Ac, Gln-14 = C-terminal amide)
Solubility:
Soluble to 1 mg/ml in water
Storage:
Desiccate at -20°C
CAS No:
197230-90-3
The technical data provided above is for guidance only.
For batch specific data refer to the Certificate of Analysis.
Tocris products are intended for laboratory research use only, unless stated otherwise.
Background References
-
A cytoplasmic peptide of the neurotrophin receptor p75NTR: induction of apoptosis and NMR determined helical conformation.
Hileman et al.
FEBS Lett., 1997;415:145
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