Biological ActivityPeptide fragment corresponding to residues 368-381 of the human p75 neurotrophin receptor (p75NTR). Forms a helical structure in the presence of micellar lipid. Induces apoptosis in human neuroblastoma cells in vitro.
(Modifications: Ala-1 = N-terminal Ac, Gln-14 = C-terminal amide)
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A cytoplasmic peptide of the neurotrophin receptor p75NTR: induction of apoptosis and NMR determined helical conformation.
Hileman et al.
FEBS Lett., 1997;415:145
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VersaClone cDNA Plasmids
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