NVP CXCR2 20
Tocris Bioscience | Catalog # 5660
Key Product Details
Description
Product Description
Potent and selective CXCR2 antagonist (IC50 = 40 nM). Exhibits selectivity for CXCR2 over a panel of 49 other GPCRs. Orally bioavailable.
Product Specifications for NVP CXCR2 20
Molecular Weight
Formula
Storage
Purity
Chemical Name
CAS Number
PubChem ID
InChI Key
SMILES
The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
Solubility
| Solvent | Max Conc. mg/mL | Max Conc. mM | |
|---|---|---|---|
| Solubility | |||
| DMSO | 15.97 | 50 |
Preparing Stock Solutions for NVP CXCR2 20
The following data is based on the product molecular weight 319.33.
Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which all affect the solvent volumes required to prepare stock solutions.
| Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
|---|---|---|---|
| 0.5 mM | 6.26 mL | 31.32 mL | 62.63 mL |
| 2.5 mM | 1.25 mL | 6.26 mL | 12.53 mL |
| 5 mM | 0.63 mL | 3.13 mL | 6.26 mL |
| 25 mM | 0.13 mL | 0.63 mL | 1.25 mL |
Calculators
Background References
References are publications that support the biological activity of the product.
- Porter The discovery of potent, orally bioavailable pyrimidine-5-carbonitrile-6-alkyl CXCR2 receptor antagonists. Bioorg.Med.Chem.Lett. 2014 PMID: 24974342
Product Documents for NVP CXCR2 20
Certificate of Analysis
To download a Certificate of Analysis, please enter a lot or batch number in the search box below.
Product Specific Notices for NVP CXCR2 20
For research use only
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