NVP CXCR2 20

   
Product Datasheet
Catalog Number:5660
Chemical Name:4-Cyclopropyl-2-[[(2,3-difluorophenyl)methyl]thio]-1,6-dihydro-6-oxo5-pyrimidinecarbonitrile
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Biological Activity
Potent and selective CXCR2 antagonist (IC50 = 40 nM). Exhibits selectivity for CXCR2 over a panel of 49 other GPCRs. Orally bioavailable.
Technical Data
  • M.Wt:
    319.33
  • Formula:
    C15H11F2N3OS
  • Solubility:
    Soluble to 50 mM in DMSO
  • Purity:
    >98
  • Storage:
    Store at +4°C
  • CAS No:
    1029521-30-9
The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis. All Tocris products are intended for laboratory research use only.
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VersaClone cDNA Plasmids
Description Application Cat# Citations Images  

Mouse CCR2 (NP_034045) VersaClone cDNA

RDC0005
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Human CCR2A (NP_001116513) VersaClone cDNA

RDC0003
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Rat CCR2 (NP_068638) VersaClone cDNA

RDC0327
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Human CCR2B (NP_001116868) VersaClone cDNA

RDC0004
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