Catalog Number: 5664
Chemical Name: Ethyl 2-[(4-chlorophenyl)amino]-4-thiazolecarboxylate
Biological Activity
Oct3/4 inducer; promotes Oct3/4 expression and stabilizes the Oct3/4 protein in HEK293 cells. Induces expression of pluripotent-associated genes Lin28, Sox2 and Nanog, and suppresses Rex1. Induces 15-fold increase in Oct3/4 expression in human primary fibroblasts.
Technical Data
  • M.Wt:
    282.75
  • Formula:
    C12H11ClN2O2S
  • Solubility:
    Soluble to 100 mM in DMSO and to 50 mM in ethanol
  • Purity:
    >98%
  • Storage:
    Store at -20°C
  • CAS No:
    165682-93-9
The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis. All Tocris products are intended for laboratory research use only.
Background References
  1. Ethyl 2-((4-Chlorophenyl)amino)thiazole-4-carboxylate and derivatives are potent inducers of Oct3/4.
    Cheng et al.
    J.Med.Chem., 2015;58:5742

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