O4I2

Key Product Details

Product Description

O4I2 is an Oct3/4 inducer; promotes Oct3/4 expression and stabilizes the Oct3/4 protein in HEK293 cells. Induces expression of pluripotent-associated genes Lin28, Sox2 and Nanog, and suppresses Rex1. Induces 15-fold increase in Oct3/4 expression in human primary fibroblasts.

Product Specifications for O4I2

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.

Solubility

Preparing Stock Solutions for O4I2

The following data is based on the product molecular weight 282.75.

Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which all affect the solvent volumes required to prepare stock solutions.

Select a batch to recalculate based on the batch molecular weight:

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Concentration / Solvent Volume / Mass	1 mg	5 mg	10 mg
1 mM	3.54 mL	17.68 mL	35.37 mL
5 mM	0.71 mL	3.54 mL	7.07 mL
10 mM	0.35 mL	1.77 mL	3.54 mL
50 mM	0.07 mL	0.35 mL	0.71 mL

Calculators

Background References

References are publications that support the biological activity of the product.

• Cheng Ethyl 2-((4-Chlorophenyl)amino)thiazole-4-carboxylate and derivatives are potent inducers of Oct3/4. J.Med.Chem. 2015 PMID: 26143659

Product Documents for O4I2