Oct3/4 inducer; promotes Oct3/4
expression and stabilizes the Oct3/4 protein in HEK293 cells. Induces expression of pluripotent-associated genes Lin28
, and suppresses Rex1
. Induces 15-fold increase in Oct3/4
expression in human primary fibroblasts.
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All Tocris products are intended for laboratory research use only.
Ethyl 2-((4-Chlorophenyl)amino)thiazole-4-carboxylate and derivatives are potent inducers of Oct3/4.
Cheng et al.