O8 OGG1 Inhibitor

Key Product Details

Product Description

O8 OGG1 Inhibitor is a potent and selective 8-oxoguanine DNA glycosylase 1 (OGG1) inhibitor (IC₅₀ = 0.2 μM in a gel based assay). Exhibits > 200-fold selectivity for OGG1 over other DNA glycosylases, NEIL1 and NTH1.

Product Specifications for O8 OGG1 Inhibitor

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.

Solubility

Preparing Stock Solutions for O8 OGG1 Inhibitor

The following data is based on the product molecular weight 261.13.

Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which all affect the solvent volumes required to prepare stock solutions.

Select a batch to recalculate based on the batch molecular weight:

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Concentration / Solvent Volume / Mass	1 mg	5 mg	10 mg
1 mM	3.83 mL	19.15 mL	38.30 mL
5 mM	0.77 mL	3.83 mL	7.66 mL
10 mM	0.38 mL	1.91 mL	3.83 mL
50 mM	0.08 mL	0.38 mL	0.77 mL

Calculators

Background References

References are publications that support the biological activity of the product. See our Citations tab to view 3 publications citing the usage of this product.

• Donley Small molecule inhibitors of 8-oxoguanine DNA glycosylase-1 (OGG1). ACS Chem.Biol. 2015 PMID: 26218629

Product Documents for O8 OGG1 Inhibitor