OB-1

Catalog # Availability Size / Price Qty
6545/10
6545/50
Cat.No. 6545 - OB-1 | C21H17N3O6 | CAS No. 300803-69-4
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Description: Stomatin-like protein-3 (STOML3) oligomerization inhibitor

Chemical Name: Ethyl 5-(1-methyl-4-nitro-1H-imidazol-5-yloxy)-2-phenylbenzofuran-3-carboxylate

Purity: ≥98%

Product Details
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Biological Activity

Stomatin-like protein-3 (STOML3) oligomerization inhibitor. Reduces STOML3 cluster size in the plasma membrane. Decreases mechanically-induced Piezo1 but not ASIC3 current amplitudes in N2a cells and cultured mouse sensory neurons in vitro. Subcutaneous administration in mice reversibly silences touch receptor activity and inhibits paw withdrawal reflex in a mouse neuropathic pain model.

Technical Data

M.Wt:
407.38
Formula:
C21H17N3O6
Solubility:
Soluble to 50 mM in DMSO
Purity:
≥98%
Storage:
Store at RT
CAS No:
300803-69-4

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis. All Tocris products are intended for laboratory research use only.

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