Chemical Name: α-(Aminomethyl)-4-hydroxybenzenemethanol hydrochloride
Biological ActivityInvertebrate biogenic amine neurotransmitter, related to noradrenalin, that is an adrenoceptor agonist. Stimulates lipolysis in mammalian adipocytes via activation of β3 receptors. Has dual effect on glucose transport in adipocytes: inhibits transport via β3 receptor activation but stimulates transport when oxidized by MAO. Also activates human α2A receptors, inhibiting subsequent cAMP production.
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Tocris products are intended for laboratory research use only, unless stated otherwise.
Dual action of octopamine on glucose transport into adipocytes: inhibition via β3-adrenoceptor activation and stimulation via oxidation by amine oxidases.
Visentin et al.
Selective inhibition of adenylyl cyclase by octopamine via a human cloned α2A-adrenoceptor.
Airriess et al.
Octopamine in invertebrates.
Selective activation of β3-adrenoceptors by octopamine: comparative studies in mammalian fat cells.
Carpene et al.
Citation for Octopamine hydrochloride
The citations listed below are publications that use Tocris products. Selected citations for Octopamine hydrochloride include:
1 Citation: Showing 1 - 1
Pericytes impair capillary blood flow and motor function after chronic spinal cord injury.
Authors: Li Et al.
Nat Med 2017;23:733
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