Octopamine hydrochloride

Key Product Details

Product Description

Invertebrate biogenic amine neurotransmitter, related to noradrenalin, that is an adrenoceptor agonist. Stimulates lipolysis in mammalian adipocytes via activation of β₃ receptors. Has dual effect on glucose transport in adipocytes: inhibits transport via β₃ receptor activation but stimulates transport when oxidized by MAO. Also activates human α_2A receptors, inhibiting subsequent cAMP production.

Product Specifications for Octopamine hydrochloride

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.

Solubility

Preparing Stock Solutions for Octopamine hydrochloride

The following data is based on the product molecular weight 189.64.

Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which all affect the solvent volumes required to prepare stock solutions.

Select a batch to recalculate based on the batch molecular weight:

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Concentration / Solvent Volume / Mass	1 mg	5 mg	10 mg
1 mM	5.27 mL	26.37 mL	52.73 mL
5 mM	1.05 mL	5.27 mL	10.55 mL
10 mM	0.53 mL	2.64 mL	5.27 mL
50 mM	0.11 mL	0.53 mL	1.05 mL

Calculators

Background References

References are publications that support the biological activity of the product. See our Citations tab to view 22 publications citing the usage of this product.

• Carpene Selective activation of β₃-adrenoceptors by octopamine: comparative studies in mammalian fat cells. Naunyn-Schmied.Arch.Pharmacol.
• Roeder Octopamine in invertebrates. Prog.Neurobiol. 1999 PMID: 10515667
• Visentin Dual action of octopamine on glucose transport into adipocytes: inhibition via β₃-adrenoceptor activation and stimulation via oxidation by amine oxidases. J.Pharmacol.Exp.Ther. 2001 PMID: 11561068
• Airriess Selective inhibition of adenylyl cyclase by octopamine via a human cloned α_2A-adrenoceptor. Br.J.Pharmacol. 1997 PMID: 9313925

Product Documents for Octopamine hydrochloride