Catalog Number: 2242
Alternate Names: (±)-p-Octopamine, Epirenor, Norfen
Chemical Name: α-(Aminomethyl)-4-hydroxybenzenemethanol hydrochloride
Biological Activity
Invertebrate biogenic amine neurotransmitter, related to noradrenalin, that is an adrenoceptor agonist. Stimulates lipolysis in mammalian adipocytes via activation of β3 receptors. Has dual effect on glucose transport in adipocytes: inhibits transport via β3 receptor activation but stimulates transport when oxidized by MAO. Also activates human α2A receptors, inhibiting subsequent cAMP production.
Technical Data
  • M.Wt:
  • Formula:
  • Solubility:
    Soluble to 100 mM in water
  • Purity:
  • Storage:
    Desiccate at RT
  • CAS No:
The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis. All Tocris products are intended for laboratory research use only.
Background References
  1. Selective inhibition of adenylyl cyclase by octopamine via a human cloned α2A-adrenoceptor.
    Airriess et al.
    Br.J.Pharmacol., 1997;122:191
  2. Octopamine in invertebrates.
    Prog.Neurobiol., 1999;59:533
  3. Dual action of octopamine on glucose transport into adipocytes: inhibition via β3-adrenoceptor activation and stimulation via oxidation by amine oxidases.
    Visentin et al.
    J.Pharmacol.Exp.Ther., 2001;299:96
  4. Selective activation of β3-adrenoceptors by octopamine: comparative studies in mammalian fat cells.
    Carpene et al.
    Naunyn-Schmied.Arch.Pharmacol., 1999;359:310
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