Octreotide

Tocris Bioscience | Catalog # 1818

sst2, sst3 and sst5 agonist
Tocris Bioscience
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Key Product Details

Description

sst2, sst3 and sst5 agonist

Alternative Names

SMS 201995,Sandostatin

Product Description

Octreotide is a peptide agonist for sst2, sst3 and sst5 somatostatin receptors. IC50/Kd values (nM) at cloned human somatostatin receptors are: 290 - 1140 (sst1), 0.4 - 2.1 (sst2), 4.4 - 34.5 (sst3), > 1000 (sst4), and 5.6 - 32 (sst5).

Product Specifications for Octreotide

Molecular Weight

1019.24

Formula

C49H66N10O10S2

Storage

Store at -20°C

Purity

≥95% (HPLC)

CAS Number

83150-76-9

PubChem ID

90488715

InChI Key

DEQANNDTNATYII-XOEBDJBESA-N

SMILES

[H]N[C@@H](CC1=CC=CC=C1)C(=O)N[C@H]1CSSC[C@H](NC(=O)[C@@H](NC(=O)[C@H](CCCCN)NC(=O)[C@H](CC2=CNC3=C2C=CC=C3)NC(=O)[C@H](CC2=CC=CC=C2)NC1=O)[C@@H](C)O)C(=O)N[C@H](CO)[C@@H](C)O

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.

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Solubility

Solubility Soluble to 1.2mg/ml in water

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Background References

References are publications that support the biological activity of the product. See our Citations tab to view 13 publications citing the usage of this product.

Product Documents for Octreotide

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot or batch number in the search box below.

Product Specific Notices for Octreotide

For research use only

Customer Reviews for Octreotide (1)

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  • Octreotide activates cAMP
    Name: Kishor Pant
    Species: Human
    Assay Type: In Vitro
    Cell Line/Tissue: HepG2, Huh, HuCCT1
    Verified Customer | Posted 04/07/2022
    Please mind that it can induce cell growth at low dose and can inhibit the cell growth at higher concentrations.
    It can activate cAMP in the cell via activating somatostatin receptors.
    Octreotide 1818

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