OD 36 hydrochloride

Catalog # Availability Size / Price Qty
OD 36 hydrochloride | CAS No. 1638644-62-8 | RIP Kinase Inhibitors
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Description: Potent RIP2 kinase inhibitor

Chemical Name: 6-Chloro-10,11,14,17-tetrahydro-13H-1,16-etheno-4,8-metheno-1H-pyrazolo[3,4-g][1,14,4,6]dioxadiazacyclohexadecine hydrochloride

Product Details

Biological Activity

Potent receptor-interacting protein kinase 2 (RIPK2) inhibitor (IC50 = 5.3 nM). Displays similar % inhibition against ALK-2 and SIK2 at 100 nM. Downregulates expression of a panel of RIPK2-dependent genes. Inhibits recruitment of inflammatory cells in a mouse MDP-induced peritonitis model.

Technical Data

Soluble to 100 mM in DMSO and to 5 mM in ethanol
Store the unopened product at room temperature. Do not use past expiration date.

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
Tocris products are intended for laboratory research use only, unless stated otherwise.

Product Datasheets

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