Chemical Name: 2-[4-Amino-6-[(phenylmethyl)amino]-1,3,5-triazin-2-yl]benzenemethanol
Biological ActivitySelective positive allosteric modulator at GPR68 (pEC50 = 6.83). Exhibits selectivity for GPR68 over 58 other GPCRs. Attenuates contextual-based fear memory in mice.
The technical data provided above is for guidance only.
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Tocris products are intended for laboratory research use only, unless stated otherwise.
Allosteric ligands for the pharmacologically dark receptors GPR68 and GPR65.
Huang et al.
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VersaClone cDNA Plasmids
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