Chemical Name: 2-[4-Amino-6-[(phenylmethyl)amino]-1,3,5-triazin-2-yl]benzenemethanol
Biological ActivitySelective positive allosteric modulator at GPR68 (pEC50 = 6.83). Exhibits selectivity for GPR68 over 58 other GPCRs. Attenuates contextual-based fear memory in mice.
The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis. All Tocris products are intended for laboratory research use only.
Allosteric ligands for the pharmacologically dark receptors GPR68 and GPR65.
Huang et al.
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VersaClone cDNA Plasmids
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