Ogerin

Key Product Details

Product Description

Ogerin is a selective positive allosteric modulator (PAM) of GPR68 (pEC₅₀ = 6.83), which exhibits selectivity for GPR68 over 58 other GPCRs. Ogerin attenuates contextual-based fear memory in mice.

External Portal Information

Chemicalprobes.org

and the Chemical Probes webpages of the Structural Genomics Consortium are portals that offer independent guidance on the selection and/or application of small molecules for research. The use of Ogerin is reviewed on chemicalprobes.org and the SGC website.

Product Specifications for Ogerin

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.

Solubility

Preparing Stock Solutions for Ogerin

The following data is based on the product molecular weight 307.35.

Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which all affect the solvent volumes required to prepare stock solutions.

Select a batch to recalculate based on the batch molecular weight:

2 1 Recalculate

Concentration / Solvent Volume / Mass	1 mg	5 mg	10 mg
1 mM	3.25 mL	16.27 mL	32.54 mL
5 mM	0.65 mL	3.25 mL	6.51 mL
10 mM	0.33 mL	1.63 mL	3.25 mL
50 mM	0.07 mL	0.33 mL	0.65 mL

Calculators

Background References

References are publications that support the biological activity of the product. See our Citations tab to view 7 publications citing the usage of this product.

• Huang Allosteric ligands for the pharmacologically dark receptors GPR68 and GPR65. Nature 2015 PMID: 26550826

Product Documents for Ogerin