Ogerin

Catalog # Availability Size / Price Qty
5722/10
5722/50
Cat.No. 5722 - Ogerin | C17H17N5O | CAS No. 1309198-71-7
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Description: Selective positive allosteric modulator at GPR68

Chemical Name: 2-[4-Amino-6-[(phenylmethyl)amino]-1,3,5-triazin-2-yl]benzenemethanol

Purity: ≥98%

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Biological Activity

Selective positive allosteric modulator at GPR68 (pEC50 = 6.83). Exhibits selectivity for GPR68 over 58 other GPCRs. Attenuates contextual-based fear memory in mice.

Technical Data

M.Wt:
307.35
Formula:
C17H17N5O
Solubility:
Soluble to 100 mM in DMSO and to 20 mM in ethanol
Purity:
≥98%
Storage:
Store at -20°C
CAS No:
1309198-71-7

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis. All Tocris products are intended for laboratory research use only.

Background References

  1. Allosteric ligands for the pharmacologically dark receptors GPR68 and GPR65.
    Huang et al.
    Nature, 2015;527:477

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