OGT 2115

Tocris Bioscience | Catalog # 2710

Antiangiogenic. Heparanase inhibitor
Tocris Bioscience

Key Product Details

Description

Antiangiogenic. Heparanase inhibitor
View all Antiangiogenic Compounds »

Product Description

OGT 2115 is a heparanase inhibitor (IC50 = 0.4 μM) that displays no major inhibition of human cytochrome P450 isoenzymes (IC50 > 30 μM). Exhibits antiangiogenic properties in vitro (IC50 = 1 μM).

Product Specifications for OGT 2115

Molecular Weight

495.30

Formula

C24H16BrFN2O4

Storage

Store at RT

Purity

≥97% (HPLC)

Chemical Name

2-[4-[[3-(4-Bromophenyl)-1-oxo-2-propenyl]amino]-3-fluorophenyl]-5-benzoxazoleacetic acid

CAS Number

853929-59-6

PubChem ID

44402523

InChI Key

LKBXWNYXDMSFQU-ONNFQVAWSA-N

SMILES

O=C(/C=C/C4=CC=C(Br)C=C4)NC(C(F)=C3)=CC=C3C2=NC1=CC(CC(O)=O)=CC=C1O2

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.

Solubility

Solvent Max Conc. mg/mL Max Conc. mM
Solubility
DMSO 4.95 10

Preparing Stock Solutions for OGT 2115

The following data is based on the product molecular weight 495.30.

Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which all affect the solvent volumes required to prepare stock solutions.

Select a batch to recalculate based on the batch molecular weight:

Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
0.1 mM 20.19 mL 100.95 mL 201.90 mL
0.5 mM 4.04 mL 20.19 mL 40.38 mL
1 mM 2.02 mL 10.09 mL 20.19 mL
5 mM 0.40 mL 2.02 mL 4.04 mL

Calculators

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Background References

References are publications that support the biological activity of the product. See our Citations tab to view 31 publications citing the usage of this product.

Product Documents for OGT 2115

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot or batch number in the search box below.

Product Specific Notices for OGT 2115

For research use only

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