OGT 2115

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2710/1
2710/10
OGT 2115 | CAS No. 853929-59-6 | Antiangiogenic Compounds
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Description: Antiangiogenic. Heparanase inhibitor

Chemical Name: 2-[4-[[3-(4-Bromophenyl)-1-oxo-2-propenyl]amino]-3-fluorophenyl]-5-benzoxazoleacetic acid

Product Details
Citations (4)
Reviews

Biological Activity

Heparanase inhibitor (IC50 = 0.4 μM) that displays no major inhibition of human cytochrome P450 isoenzymes (IC50 > 30 μM). Exhibits antiangiogenic properties in vitro (IC50 = 1 μM).

Technical Data

Formula:
C24H16BrFN2O4
Solubility:
Soluble to 10 mM in DMSO
Storage:
Store the unopened product at room temperature. Do not use past expiration date.
CAS No:
853929-59-6

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
Tocris products are intended for laboratory research use only, unless stated otherwise.

Background References

  1. Heparanase: a target for drug discovery in cancer and inflammation.
    McKenzie
    Br.J.Pharmacol., 2007;151:1
  2. Furanyl-1,3-thiazol-2-yl and benzoxazol-5-yl acetic acid derivates: novel classes of heparanase inhibitor.
    Courtney et al.
    Bioorg.Med.Chem.Letts., 2005;15:2295

Product Datasheets

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Citations for OGT 2115

The citations listed below are publications that use Tocris products. Selected citations for OGT 2115 include:

4 Citations: Showing 1 - 4

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