Oligomycin A

Tocris Bioscience | Catalog # 4110

Inhibitor of mitochondrial ATPase
Tocris Bioscience

Key Product Details

Description

Inhibitor of mitochondrial ATPase
View all Other ATPase Inhibitors »

Product Description

Oligomycin A is an inhibitor of mitochondrial ATP synthase and uncoupler of oxidative phosphorylation. Antibiotic; exhibits anti-tumor activity.

Product Specifications for Oligomycin A

Molecular Weight

791.06

Formula

C45H74O11

Storage

Store at -20°C

Purity

≥98% (HPLC)

Chemical Name

(1R,4E,5'S,6S,6'S,7R,8S,10R,11R, 12S,14R,15S,16R,18E,20E,22R,25S,27R,28S,29R)-22-ethyl-7,11,14,15-tetrahydroxy-6'-[(2R)-2-hydroxypropyl]-5',6,8,10,12,14,16,28,29-nonamethyl-3',4',5',6'-tetrahydro-3H,9H,13H-spiro[2,26-dioxabicyclo[23.3.1]nonacosa-4,18,20-triene-27,2'-pyran]-3,9,13-trione

CAS Number

579-13-5

PubChem ID

5281899

InChI Key

MNULEGDCPYONBU-WMBHJXFZSA-N

SMILES

CC[C@](CC[C@@]([H])(O[C@@]2(CC[C@@H](C)[C@@]([H])(C[C@@H](O)C)O2)[C@@H]1C)[C@H](C)[C@]1([H])OC(/C=C/[C@H]([C@@H]([C@@H](C)C([C@@H](C)[C@H](O)[C@H]3C)=O)O)C)=O)([H])/C=C/C=C/C[C@H](C)[C@@H](O)[C@](C)(O)C3=O

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.

Solubility

Solvent Max Conc. mg/mL Max Conc. mM
Solubility
Ethanol 7.91 10

Preparing Stock Solutions for Oligomycin A

The following data is based on the product molecular weight 791.06.

Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which all affect the solvent volumes required to prepare stock solutions.

Select a batch to recalculate based on the batch molecular weight:

Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
0.1 mM 12.64 mL 63.21 mL 126.41 mL
0.5 mM 2.53 mL 12.64 mL 25.28 mL
1 mM 1.26 mL 6.32 mL 12.64 mL
5 mM 0.25 mL 1.26 mL 2.53 mL

Calculators

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Background References

References are publications that support the biological activity of the product. See our Citations tab to view 39 publications citing the usage of this product.

Product Documents for Oligomycin A

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot or batch number in the search box below.

Product Specific Notices for Oligomycin A

For research use only

Customer Reviews for Oligomycin A (1)

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  • Oligomycin A was used in oxidative phosphorylation studies
    Name: Jade Smith
    Species: Mouse
    Assay Type: In Vivo
    Verified Customer | Posted 02/05/2019
    Oligomycin A was used in oxidative phosphorylation studies. Its action on protein channel blocking was being studied. Performed well and gives repeatable results.
    Oligomycin A 4110

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