Oligomycin A

Catalog # Availability Size / Price Qty
4110/5
Oligomycin A | CAS No. 579-13-5 | Other ATPase Inhibitors
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Description: Inhibitor of mitochondrial ATPase

Chemical Name: (1R,4E,5'S,6S,6'S,7R,8S,10R,11R, 12S,14R,15S,16R,18E,20E,22R,25S,27R,28S,29R)-22-ethyl-7,11,14,15-tetrahydroxy-6'-[(2R)-2-hydroxypropyl]-5',6,8,10,12,14,16,28,29-nonamethyl-3',4',5',6'-tetrahydro-3H,9H,13H-spiro[2,26-dioxabicyclo[23.3.1]nonacosa-4,18,20-triene-27,2'-pyran]-3,9,13-trione

Purity: ≥95%

Product Details
Citations (3)
Reviews (1)

Biological Activity

Inhibitor of mitochondrial ATP synthase and uncoupler of oxidative phosphorylation. Antibiotic; exhibits anti-tumor activity.

Technical Data

M.Wt:
791.06
Formula:
C45H74O11
Solubility:
Soluble to 10 mM in ethanol
Purity:
≥95%
Storage:
Store at -20°C
CAS No:
579-13-5

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
Tocris products are intended for laboratory research use only, unless stated otherwise.

Background References

  1. Apoptolidin, a selective cytotoxic agent, is an inhibitor of F0F1-ATPase.
    Salomon et al.
    Chem.Biol., 2001;8:71

Product Datasheets

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Citations for Oligomycin A

The citations listed below are publications that use Tocris products. Selected citations for Oligomycin A include:

3 Citations: Showing 1 - 3

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Reviews for Oligomycin A

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Oligomycin A was used in oxidative phosphorylation studies
By Jade Smith on 02/05/2019
Species: Mouse

Oligomycin A was used in oxidative phosphorylation studies. Its action on protein channel blocking was being studied. Performed well and gives repeatable results.


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