Olmesartan

Catalog # Availability Size / Price Qty
4616/50
Cat.No. 4616 - Olmesartan | C24H26N6O3 | CAS No. 144689-24-7
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Description: Potent AT1 antagonist; metabolite of Olmesartan medoxomil (Cat. No. 4620)

Chemical Name: 4-(1-Hydroxy-1-methylethyl)-2-propyl-1-[[2'-(2H-tetrazol-5-yl)[1,1'-biphenyl]-4-yl]methyl]-1H-imidazole-5-carboxylic acid

Purity: ≥99%

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Biological Activity

Potent angiotensin II type I (AT1) receptor antagonist (IC50 = 6.7 nM at hAT1 receptors). Improves cognitive function in a mouse model of hypertension- and hyperlipidemia-associated cognitive decline; ameliorates arterial stiffness in a rat model of chronic renal failure. Metabolite of Olmesartan medoxomil (Cat. No. 4620).

Technical Data

M.Wt:
446.5
Formula:
C24H26N6O3
Solubility:
Soluble to 20 mM in DMSO
Purity:
≥99%
Storage:
Store at +4°C
CAS No:
144689-24-7

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
Tocris products are intended for laboratory research use only, unless stated otherwise.

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