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Oncrasin 1

   
Product Datasheet
Catalog Number:3427
Chemical Name:1-[(4-Chlorophenyl)methyl]-1H-indole-3-carboxaldehyde
Product Details
Reviews
Biological Activity
Proapoptotic agent that induces abnormal nuclear aggregation of PKCι and suppresses RNA transcription. Exhibits antiproliferative effects against various human tumor cell lines with K-Ras mutations (IC50 ≤ 3 μM) with minimal effects on normal epithelial cells and inhibits human xenograft growth by 75% in vivo.
Technical Data
  • M.Wt:
    269.73
  • Formula:
    C16H12ClNO
  • Solubility:
    Soluble to 100 mM in DMSO and to 25 mM in ethanol
  • Purity:
    >98
  • Storage:
    Store at +4°C
  • CAS No:
    75629-57-1
The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis. All Tocris products are intended for laboratory research use only.
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