Chemical Name: 1-(2,4-Dihydroxyphenyl)-2-(4-methoxyphenyl)ethanone
Biological ActivityOnonetin is a naturally occurring deoxybenzoin. TRPM3 channel blocker (IC50 = 300 nM). Inhibits pregnenolone sulfate-induced intracellular Ca2+ accumulation in HEKmTRPM3 cells and dorsal root ganglia (DRG) neurons in vitro.
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Tocris products are intended for laboratory research use only, unless stated otherwise.
Citrus fruit and fabacea secondary metabolites potently and selectively block TRPM3.
Straub et al.
Citation for Ononetin
The citations listed below are publications that use Tocris products. Selected citations for Ononetin include:
1 Citation: Showing 1 - 1
Hypotonic stress induces RANKL via transient receptor potential melastatin 3 (TRPM3) and vaniloid 4 (TRPV4) in human PDL cells.
Authors: Son Et al.
J Dent Res 2015;94:473
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