Catalog Number: 4447
Chemical Name: N-Methyl-N-[(3R)-3-phenyl-3-[4-(trifluoromethyl)phenoxy]propyl]-glycine
Biological Activity
Inhibitor of the glial glycine transporter (GlyT1); derivative of Org 24598 (Cat. No. 4035).
Technical Data
  • M.Wt:
    367.36
  • Formula:
    C19H20F3NO3
  • Solubility:
    Soluble to 10 mM in water with gentle warming and to 100 mM in DMSO
  • Purity:
    >98%
  • Storage:
    Store at +4°C
  • CAS No:
    372198-97-5
The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis. All Tocris products are intended for laboratory research use only.
Background References
  1. Glycine reuptake inhibition as a new therapeutic approach in schizophrenia: focus on the glycine transporter 1 (GlyT1).
    Chue et al.
    Curr.Pharm.Des., 2013;19:1311
  2. Discovery and SAR of org 24598-a selective glycine uptake inhibitor.
    Brown et al.
    Bioorg.Med.Chem.Lett., 2001;11:2007
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