Orphanin FQ (1-11)
Tocris Bioscience | Catalog # 3932
Potent NOP agonist; displays analgesic properties
Discontinued Product
3932 has been discontinued.
View all NOP Receptor Agonists products.
Key Product Details
Description
Potent NOP agonist; displays analgesic properties
Alternative Names
Nociceptin (1-11)
Product Description
Orphanin FQ (1-11) is a peptide fragment containing amino acids 1-11 of Nociceptin (Cat. No. 0910). Potent agonist of the ORL1/KOR-3 receptor (Ki = 55 nM); displays no affinity for opioid receptors, including μ, δ, κ1 and κ3 receptors (Ki >1000 nM). Displays analgesic properties in CD-1 mice.
Product Specifications for Orphanin FQ (1-11)
Molecular Weight
1098.20
Formula
C49H75N15O14
Storage
Store at -20°C
CAS Number
178249-41-7
PubChem ID
10653748
InChI Key
BBTOUBACUUPBRQ-KCKZSKPYSA-N
SMILES
[H]N[C@@H](CC1=CC=CC=C1)C(=O)NCC(=O)NCC(=O)N[C@@H](CC1=CC=CC=C1)C(=O)N[C@@H]([C@@H](C)O)C(=O)NCC(=O)N[C@@H](C)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CO)C(=O)N[C@@H](C)C(O)=O
The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
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Solubility
| Solubility | Soluble to 2mg/ml in 20% acetonitrile / water |
Calculators
Background References
References are publications that support the biological activity of the product.
- Rossi Orphanin FQ/nociceptin analgesia in the rat. Brain Res. 1998 PMID: 9593974
- Reinscheid Structure-activity relationship studies on the novel neuropeptide orphanin FQ. J.Biol.Chem. 1996 PMID: 8662940
- Rossi Pharmacological characterization of orphanin FQ/nociceptin and its fragments. J.Pharmacol.Exp.Ther. 1997 PMID: 9262352
Product Documents for Orphanin FQ (1-11)
Certificate of Analysis
To download a Certificate of Analysis, please enter a lot or batch number in the search box below.
Product Specific Notices for Orphanin FQ (1-11)
For research use only
Related Research Areas
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