OS9 Antibody Blocking Peptide

Name: OS9 Antibody Blocking Peptide
Brand: Novus Biologicals
SKU: BC100-520PEP
Price: 99 USD
Availability: InStock

Novus Biologicals | Catalog # BC100-520PEP

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Product Specifications
Preparation & Storage
Background
Product Documents
Specific Notices

Key Product Details

Applications

Antibody Competition

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Product Specifications

Description

A OS9 antibody blocking peptide.

Application Notes

This peptide is useful as a blocking peptide for BC100-520. For further blocking peptide related protocol, click here.

Specificity

This peptide is specific for BC100-520 only.

Protein / Peptide Type

Antibody Blocking Peptide

Formulation, Preparation, and Storage

BC100-520PEP

Formulation	Peptide dissolved in dH2O. Contains no BSA.
Preservative	No Preservative
Concentration	1.0 mg/ml
Shipping	The product is shipped with dry ice or equivalent. Upon receipt, store it immediately at the temperature recommended below.
Stability & Storage	Store at -80C. Avoid freeze-thaw cycles.

Background: OS9

OS9 is a lectin which functions in endoplasmic reticulum quality control and ER-associated degradation. This ER glycoprotein is found in the intralumenal level and highly expressed in tumor tissue. The OS9 gene is transcriptionally induced upon activation of the Ire1/Xbp1 ER-stress pathway.

Functionally, OS9 binds to HIF-1, a key regulator of the hypoxic response and angiogenesis, and promotes the degradation of one of its subunits. It may also bind terminally misfolded non-glycosylated proteins as well as improperly folded glycoproteins, retain them in the ER, and possibly transfer them to the ubiquitination machinery and promote their degradation. One such possible target includes TRPV4.

Alternate Names

Amplified in osteosarcoma 9, endoplasmic reticulum lectin 2, ERLEC2, erlectin 2, OS-9, osteosarcoma amplified 9, endoplasmic reticulum associated protein, osteosarcoma amplified 9, endoplasmic reticulum lectin, protein OS-9

Gene Symbol

OS9

Additional OS9 Products

Product Documents for OS9 Antibody Blocking Peptide

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Certificate of Analysis

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Product Specific Notices for OS9 Antibody Blocking Peptide

This product is for research use only and is not approved for use in humans or in clinical diagnosis. This product is guaranteed for 1 year from date of receipt.

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