Recombinant Human OSCAR His Protein

Novus Biologicals | Catalog # NBP2-23312

Novus Biologicals
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Key Product Details

Source

E. coli

Tag

His

Applications

SDS-PAGE
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Product Specifications

Description

A denatured recombinant protein with a N-Terminal His-tag and corresponding to the amino acids 19-286 of Human OSCAR

Source: E.coli

Amino Acid Sequence: MGSSHHHHHH SSGLVPRGSH MGSDITPSVA IIVPPASYHP KPWLGAQPAT VVTPGVNVTL RCRAPQPAWR FGLFKPGEIA PLLFRDVSSE LAEFFLEEVT PAQGGIYRCC YRRPDWGPGV WSQPSDVLEL LVTEELPRPS LVALPGPVVG PGANVSLRCA GRLRNMSFVL YREGVAAPLQ YRHSAQPWAD FTLLGARAPG TYSCYYHTPS APYVLSQRSE VLVISWEGEG PEARPASSAP GMQAPGPPPS DPGAQAPSLS SFRPRGLVLQ PLLPQTQDSW DPAPPPSDPG V

Purity

>85%, by SDS-PAGE

Predicted Molecular Mass

31.2 kDa.
Disclaimer note: The observed molecular weight of the protein may vary from the listed predicted molecular weight due to post translational modifications, post translation cleavages, relative charges, and other experimental factors.

Application Notes

Denatured protein is most likely not the best option for functional studies. It is better suited for Western Blot (WB) or imaging assays.

Protein / Peptide Type

Recombinant Protein

Scientific Data Images for Recombinant Human OSCAR His Protein

SDS-PAGE: Recombinant Human OSCAR His Protein [NBP2-23312]

SDS-PAGE: Recombinant Human OSCAR His Protein [NBP2-23312]

SDS-Page: Recombinant Human OSCAR His Protein [NBP2-23312] - 3ug by SDS-PAGE under reducing condition and visualized by coomassie blue stain.

Formulation, Preparation, and Storage

NBP2-23312
Formulation 20 mM Tris-HCl buffer (pH 8.0), 0.4M UREA, 10% glycerol
Preservative No Preservative
Concentration 0.25 mg/ml
Shipping The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.
Stability & Storage Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.

Background: OSCAR

Osteoclasts are multinucleated cells that resorb bone and are essential for bone homeostasis. OSCAR is a member of the leukocyte receptor complex (LRC) protein family that plays critical roles in the regulation of both innate and adaptive immune responses. Different from the other LRC members, OSCAR expression is detected specifically in preosteoclasts or mature osteoclasts. OSCAR may be an important bone-specific regulator of osteoclast differentiation. Multiple alternatively spliced transcript variants encoding different isoforms have been found for this gene. Recombinant human OSCAR protein, fused to His-tag at N-terminus, was expressed in E.coli.

Long Name

Osteoclast-associated Receptor

Alternate Names

hOSCAR, MGC33613, osteoclast associated receptor OSCAR-S1, osteoclast associated receptor OSCAR-S2, osteoclast associated, immunoglobulin-like receptor, osteoclast-associated immunoglobulin-like receptor, Osteoclast-associated receptor, PIGR3, PIgR-3, Poly-Ig receptor 3, Polymeric immunoglobulin receptor 3

Gene Symbol

OSCAR

Additional OSCAR Products

Product Documents for Recombinant Human OSCAR His Protein

Certificate of Analysis

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Product Specific Notices for Recombinant Human OSCAR His Protein

This product is for research use only and is not approved for use in humans or in clinical diagnosis. This product is guaranteed for 1 year from date of receipt.

Related Research Areas

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