OUL 35

Key Product Details

Product Description

OUL 35 is a selective PARP-10 (also known as ADP-ribosyltransferase Diptheria Toxin-like 10, ARTD10) inhibitor (IC₅₀ = 0.329 μM). Displays selectivity for PARP-10 over a panel of PARP family members. Rescues HeLa cells from PARP-10-induced cell death. Sensitizes cancer cells to hydroxyurea-induced genotoxic stress.

Product Specifications for OUL 35

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.

Solubility

Preparing Stock Solutions for OUL 35

The following data is based on the product molecular weight 256.26.

Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which all affect the solvent volumes required to prepare stock solutions.

Select a batch to recalculate based on the batch molecular weight:

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Concentration / Solvent Volume / Mass	1 mg	5 mg	10 mg
1 mM	3.90 mL	19.51 mL	39.02 mL
5 mM	0.78 mL	3.90 mL	7.80 mL
10 mM	0.39 mL	1.95 mL	3.90 mL
50 mM	0.08 mL	0.39 mL	0.78 mL

Calculators

Background References

References are publications that support the biological activity of the product. See our Citations tab to view 5 publications citing the usage of this product.

• Venkannagari Small-molecule chemical probe rescues cells from mono-ADP-ribosyltransferase ARTD10/PARP10-induced apoptosis and sensitizes cancer cells to DNA damage. Cell Chem.Biol. 2016 PMID: 27667561

Product Documents for OUL 35