Biological ActivityOxytocin is a neurohypophyseal peptide. Stimulates uterine contraction and lactation.
(Modifications: Gly-9 = C-terminal amide, Disulfide bridge between 1 - 6)
The technical data provided above is for guidance only.
For batch specific data refer to the Certificate of Analysis.
Tocris products are intended for laboratory research use only, unless stated otherwise.
Vasopressin and oxyt. receptors in the central nervous system.
Barberis and Tribolle
Signal transduction pathways of the human V1-vascular V2-renal, V3-pituitary vasopressin and oxyt. receptors.
Thibonnier et al.
Prog.Brain Res., 1998;119:147
Citations for Oxytocin
The citations listed below are publications that use Tocris products. Selected citations for Oxytocin include:
6 Citations: Showing 1 - 6
Central and peripheral GLP-1 systems independently and additively suppress eating.
Authors: Brierley Et al.
Nat Metab 2021;3:258
OXT can regulate myometrial smooth muscle excitability by inhibiting the Na+ -activated K+ channel, Slo2.1.
Authors: Ferreira Et al.
J Physiol 2019;597:137
OXT functions as a spatiotemporal filter for excitatory synaptic inputs to VTA DA neurons.
Authors: Xiao Et al.
Targeted Interneuron Depletion in the Dorsal Striatum Produces Autism-like Behavioral Abnormalities in Male but Not Female Mice.
Authors: Rapanelli Et al.
Biol Psychiatry 2017;82:194
The orphan G protein-coupled receptor GPR139 is activated by the peptides: Adrenocorticotropic hormone (ACTH), α-, and β-melanocyte stimulating hormone (α-MSH, and β-MSH), and the conserved core motif HFRW.
Authors: Nøhr Et al.
Neurochem Int 2017;102:105
Serotonergic neuron regulation informed by in vivo single-cell transcriptomics.
Authors: Spaethling Et al.
No product specific FAQs exist for this product, however you mayView all Peptide FAQs
VersaClone cDNA Plasmids
Reviews for Oxytocin
Average Rating: 4.5 (Based on 2 Reviews)
Have you used Oxytocin?
Submit a review and receive an Amazon gift card.
$25/€18/£15/$25CAN/¥75 Yuan/¥1250 Yen for a review with an image
$10/€7/£6/$10 CAD/¥70 Yuan/¥1110 Yen for a review without an image
Preincubation of slices in oxytocin (200 nM) resulted in an increase in holding current when compared to slices incubated in normal ACSF.
Applied to rat uterus and human smooth muscle