P-3FAX-Neu5Ac

Catalog # Availability Size / Price Qty
5760/10
Cat.No. 5760 - P-3FAX-Neu5Ac | C22H30FNO14 | CAS No. 117405-58-0
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Description: Sialic acid analog; sialyltransferase inhibitor

Chemical Name: 5-(acetylamino)-3,5-dideoxy-3-fluoro-D-erythro-α-L-manno-2-nonulopyranosonic acid methyl ester 2,4,7,8,9-pentaacetate

Purity: ≥97%

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Biological Activity

Cell-permeable sialic acid analog. Deacetylation occurs intracellularly giving rise to a sialyltransferase inhibitor. Abolishes expression of SLex expression on HL-60 cells and reduces E-selectin and P-selectin binding. Prevents metastasis formation in a mouse lung metastasis model.

Technical Data

M.Wt:
551.47
Formula:
C22H30FNO14
Solubility:
Soluble to 100 mM in DMSO and to 50 mM in ethanol
Purity:
≥97%
Storage:
Store at -20°C
CAS No:
117405-58-0

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis. All Tocris products are intended for laboratory research use only.

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