Biological ActivityBinds irreversibly to tryptophan hydroxylase to cause depletion of serotonin in the brain.
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Effect of p-chlorophenylalanine at moderate dosage on 5-HT and 5-HIAA concentrations in brain regions of control and p-chloroamphetamine treated rats.
Datla and Curzon
The effects of DL-p-chlorophenylalanine and DL-α-methyl-p-tyrosine on the brain catecholamine, serotonin and free amino acid contents in rat.
Koyuncuoglu et al.
Citations for p-Chlorophenylalanine
The citations listed below are publications that use Tocris products. Selected citations for p-Chlorophenylalanine include:
2 Citations: Showing 1 - 2
NAD+ protects against EAE by regulating CD4+ T-cell differentiation.
Authors: Tullius Et al.
Nat Commun 2014;5:5101
Mammary gland serotonin regulates parathyroid hormone-related protein and other bone-related signals.
Authors: Hernandez Et al.
Proc Natl Acad Sci U S A 2012;302:E1009
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