P110

Tocris Bioscience | Catalog # 6897

Dynamin-related protein 1 (Drp1) inhibitor; cell-permeable
Tocris Bioscience

Key Product Details

Description

Dynamin-related protein 1 (Drp1) inhibitor; cell-permeable
View all Dynamin Inhibitors »

Product Description

P110 is a dynamin-related protein 1 (Drp1) inhibitor, inhibits Drp1 GTPase activity. Displays no effect on dynamin 1 or other mitochondrial dynamics-related proteins. Inhibits mitochondrial fission, dysfunction and reactive oxygen species (ROS) production in vitro. Reduces programmed cell death and improves cell viability by protecting mitochondrial integrity. Reduces mitochondrial fragmentation and mitochondrial ROS production in mouse model of Parkinson's disease. Cell permeable.

Product Specifications for P110

Molecular Weight

2411.80

Formula

C100H179N45O25

Storage

Store at -20°C

Purity

≥95% (HPLC)

CAS Number

2770267-63-3

InChI Key

TYQHBBMTJWPEDH-VZOPDNRXSA-N

SMILES

[H]N[C@H](C(NCC(N[C@H](C(N[C@H](C(N[C@H](C(N[C@H](C(N[C@H](C(N[C@H](C(N[C@H](C(N[C@H](C(N[C@H](C(NCC(NCC(N[C@H](C(N[C@H](C(N[C@H](C(N1CCC[C@H]1C(N[C@H](C(NCC(N[C@H](C(N)=O)CO)=O)=O)CCCNC(N)=N)=O)=O)CC(C)C)=O)CC(C)C)=O)CC(O)=O)=O)=O)=O)CCCNC(N)=N)=O)CCCNC(N)=N)=O)CCCNC(N)=N)=O)CCC(N)=O)=O)CCCNC(N)=N)=O)CCCNC(N)=N)=O)CCCCN)=O)CCCCN)=O)CCCNC(N)=N)=O)=O)CC2=CC=C(C=C2)O

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.

Solubility

Solubility Soluble to 1mg/ml in water

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Background References

References are publications that support the biological activity of the product. See our Citations tab to view 9 publications citing the usage of this product.

Product Documents for P110

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot or batch number in the search box below.

Product Specific Notices for P110

For research use only

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