p130Cas/BCAR1 Antibody - BSA Free

Novus Biologicals | Catalog # NBP2-34076

Novus Biologicals
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Key Product Details

Species Reactivity

Validated:

Human, Mouse

Predicted:

Rat (93%). Backed by our 100% Guarantee.

Applications

Immunohistochemistry, Immunohistochemistry-Paraffin, Western Blot

Label

Unconjugated

Antibody Source

Polyclonal Rabbit IgG

Format

BSA Free
View all p130Cas Primary Antibodies »

Product Specifications

Immunogen

This antibody was developed against a recombinant protein corresponding to amino acids: SPQFQSPPAKQTSTFSKQTPHHPFPSPATDLYQVPPGPGGPAQDIYQVPPSAGMGHDIYQVPPSMDTRSWEGTKPPAKVVVPTRVGQGYVYEAAQPEQDEYD

Clonality

Polyclonal

Host

Rabbit

Isotype

IgG

Scientific Data Images for p130Cas/BCAR1 Antibody - BSA Free

Western Blot: p130Cas/BCAR1 Antibody [NBP2-34076]

Western Blot: p130Cas/BCAR1 Antibody [NBP2-34076]

Western Blot: p130Cas/BCAR1 Antibody [NBP2-34076] - Analysis in human spleen tissue.
Immunohistochemistry: p130Cas/BCAR1 Antibody [NBP2-34076]

Immunohistochemistry: p130Cas/BCAR1 Antibody [NBP2-34076]

Immunohistochemistry: p130Cas/BCAR1 Antibody [NBP2-34076] - Staining of mouse forebrain shows moderate labelling of cells in the lateral septum
Immunohistochemistry-Paraffin: p130Cas/BCAR1 Antibody [NBP2-34076]

Immunohistochemistry-Paraffin: p130Cas/BCAR1 Antibody [NBP2-34076]

Immunohistochemistry-Paraffin: p130Cas/BCAR1 Antibody [NBP2-34076] - Staining of human cerebellum shows strong cytoplasmic staining in Purkinje cell.
Immunohistochemistry-Paraffin: p130Cas/BCAR1 Antibody [NBP2-34076]

Immunohistochemistry-Paraffin: p130Cas/BCAR1 Antibody [NBP2-34076]

Immunohistochemistry-Paraffin: p130Cas/BCAR1 Antibody [NBP2-34076] - Staining of human rectum shows strong cytoplasmic positivity in glandular cells.
Immunohistochemistry: p130Cas/BCAR1 Antibody [NBP2-34076]

Immunohistochemistry: p130Cas/BCAR1 Antibody [NBP2-34076]

Immunohistochemistry: p130Cas/BCAR1 Antibody [NBP2-34076] - Staining of mouse cerebellum shows positivity in purkinje cells and their dendrites
Immunohistochemistry: p130Cas/BCAR1 Antibody [NBP2-34076]

Immunohistochemistry: p130Cas/BCAR1 Antibody [NBP2-34076]

Immunohistochemistry: p130Cas/BCAR1 Antibody [NBP2-34076] - Staining of mouse olfactory bulb shows immunoreactivity in mitral and periglomerular cells.

Applications for p130Cas/BCAR1 Antibody - BSA Free

Application
Recommended Usage

Immunohistochemistry

1:50 - 1:200

Immunohistochemistry-Paraffin

1:50 - 1:200

Western Blot

0.04-0.4 ug/ml
Application Notes
For IHC-Paraffin, HIER pH 6 retrieval is recommended.

Formulation, Preparation, and Storage

Purification

Affinity purified

Formulation

PBS (pH 7.2) and 40% Glycerol

Format

BSA Free

Preservative

0.02% Sodium Azide

Concentration

Concentrations vary lot to lot. See vial label for concentration. If unlisted please contact technical services.

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.

Background: p130Cas

BCAR1/p130CAS functions as a scaffolding protein for components of various kinase signaling pathways. It is involved in integrin signaling for cell motility as well as netrin signaling for the guidance of commissural axons. Overexpression of BCAR1/p130CAS has been shown to confer antiestrogen resistance in breast cancer cells. Alternate names for BCAR1/p130CAS include breast cancer anti-estrogen resistance protein 1, CRK-associated substrate, CAS scaffolding protein family member 1, CAS, and CRKAS.

Long Name

Breast Cancer Anti-estrogen Resistance 1

Alternate Names

BCAR1, CASS1, CRKAS

Gene Symbol

BCAR1

UniProt

P56945

Additional p130Cas Products

Product Documents for p130Cas/BCAR1 Antibody - BSA Free

Certificate of Analysis

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Product Specific Notices for p130Cas/BCAR1 Antibody - BSA Free

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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Protocols

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FAQs

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