PAF (C16)

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2940/1
PAF (C16) | CAS No. 74389-68-7 | Platelet-activating Factor (PAF) Receptor Agonists
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Description: Endogenous platelet-activating factor (PAF)
Alternative Names: Platelet-activating factor

Chemical Name: (7R)-7-(Acetyloxy)-4-hydroxy-N,N,N-trimethyl-3,5,9-trioxa-4-phosphapentacosan-1-aminium-4-oxide

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Biological Activity

Endogenous platelet-activating factor (PAF) and ligand for PAF receptors. Produced by inflammatory cells and a potent chemoattractant for polymorphonuclear neutrophils. Induces increased vascular permeability.

Technical Data

M.Wt:
523.68
Formula:
C26H54NO7P
Solubility:
Soluble to 100 mM in water and to 100 mM in ethanol
Storage:
Desiccate at -20°C
CAS No:
74389-68-7

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
Tocris products are intended for laboratory research use only, unless stated otherwise.

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Platelet activating factor (PAF)
By Anonymous on 05/02/2018
Application: Species: Human

Platelet activating factor (PAF) at 100nM induced a biphasic calcium response in microglia culture. Initial release from internal source and subsequent a sustained influx.


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