Catalog Number: 4637
Biological Activity
Toll-like receptor 2/6 (TLR2/6) agonist. Induces TNF-α production in human mononuclear cells. Also induces proliferation and activation of mouse splenic B cells.
Technical Data
  • M.Wt:
  • Formula:
  • Sequence:

    (Modifications: Cys = S-[2,3-Bis(palmitoyloxy)-(2-R)-propyl]-Cys)

  • Solubility:
    Soluble to 1 mg/ml in 0.25% acetic acid
  • Storage:
    Store at -20°C
  • CAS No:
The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis. All Tocris products are intended for laboratory research use only.
Background References
  1. Toll-like receptor agonists synergize with CD40L to induce either proliferation or plasma cell differentiation of mouse B cells.
    Boeglin et al.
    PLoS One, 2011;6:e25542
  2. Domain exchange between human Toll-like receptors 1 and 6 reveals a region required for lipopeptide discrimination.
    Omueti et al.
    J.Biol.Chem., 2005;280:36616
  3. Physiochemical and biological analysis of synthetic bacterial lipopeptides: validity of the concept of endotoxic conformation.
    Schromm et al.
    J.Biol.Chem., 2007;282:11030
Tocris Peptides
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Pam2CSK4 Biotin

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