Catalog Number: 4637
Biological Activity
Toll-like receptor 2/6 (TLR2/6) agonist. Induces TNF-α production in human mononuclear cells. Also induces proliferation and activation of mouse splenic B cells.
Technical Data
  • M.Wt:
    1271.83
  • Formula:
    C65H126N10O12S
  • Sequence:
    CSKKKK

    (Modifications: Cys = S-[2,3-Bis(palmitoyloxy)-(2-R)-propyl]-Cys)

  • Solubility:
    Soluble to 1 mg/ml in 0.25% acetic acid
  • Storage:
    Store at -20°C
  • CAS No:
    868247-72-7
The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis. All Tocris products are intended for laboratory research use only.
Background References
  1. Toll-like receptor agonists synergize with CD40L to induce either proliferation or plasma cell differentiation of mouse B cells.
    Boeglin et al.
    PLoS One, 2011;6:e25542
  2. Domain exchange between human Toll-like receptors 1 and 6 reveals a region required for lipopeptide discrimination.
    Omueti et al.
    J.Biol.Chem., 2005;280:36616
  3. Physiochemical and biological analysis of synthetic bacterial lipopeptides: validity of the concept of endotoxic conformation.
    Schromm et al.
    J.Biol.Chem., 2007;282:11030
Tocris Peptides
Description Application Cat# Citations Images  

Pam2CSK4 Biotin

4638  
View Sizes & Prices
Catalog# Size Price Stock Quantity
Loading Information....

Have you used Pam2CSK4?

Submit a review and receive a $25US/€18/£15/$25CAN amazon gift card if you include an image - $10US/€7/£6/$10CAN Amazon card for reviews without an image. Limited to verified customers in USA, Canada and Europe.

Tocris Bioscience is the leading supplier of novel and exclusive tools for life science research with over 30 years' experience in the industry. Tocris is a Bio-Techne brand.

Order Details

Note:

Contact Information

Calculators

Molarity Calculator

Calculate the mass, volume, or concentration required for a solution.
=
x
x
g/mol

*When preparing stock solutions always use the batch-specific molecular weight of the product found on the vial label and SDS / CoA (available online).

R&D Systems Guarantee

or select another batch: 

Feedback

Customer Information