Pam2CSK4

Catalog # Availability Size / Price Qty
4637/1
Toll-like Receptor Agonists Peptide
1 Image
Description: TLR2/6 agonist; induces TNF-α production
Product Details
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Reviews (1)

Biological Activity

Toll-like receptor 2/6 (TLR2/6) agonist. Induces TNF-α production in human mononuclear cells. Also induces proliferation and activation of mouse splenic B cells.

Technical Data

M.Wt:
1271.83
Formula:
C65H126N10O12S
Sequence:
CSKKKK

(Modifications: Cys = S-[2,3-Bis(palmitoyloxy)-(2-R)-propyl]-Cys)

Solubility:
Soluble to 1 mg/ml in 0.25% acetic acid
Storage:
Store at -20°C
CAS No:
868247-72-7

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
Tocris products are intended for laboratory research use only, unless stated otherwise.

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Pam2CSK4 induces TNFa production and release
By Anonymous on 12/12/2018
Species: Mouse

Raw macrophages were stimulated either with LPS (200 ng/ml) or Pam2CSK4 (50 nM) for 8 h to follow TNFa concentration in cell culture medium using ELISA. Pam2CSK4 induced TNFa production and release in a similar extent as LPS.


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