Toll-like receptor 2/6 (TLR2/6) agonist. Induces TNF-α
production in human mononuclear cells. Also induces proliferation and activation of mouse splenic B cells.
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Toll-like receptor agonists synergize with CD40L to induce either proliferation or plasma cell differentiation of mouse B cells.
Boeglin et al.
PLoS One, 2011;6:e25542
Domain exchange between human Toll-like receptors 1 and 6 reveals a region required for lipopeptide discrimination.
Omueti et al.
Physiochemical and biological analysis of synthetic bacterial lipopeptides: validity of the concept of endotoxic conformation.
Schromm et al.