Pam3CSK4

Catalog # Availability Size / Price Qty
4633/1
Pam3CSK4
1 Image
Description: TLR1/2 agonist; induces cytokine production
Product Details
Supplemental Products
Reviews (2)

Biological Activity

Toll-like receptor 1/2 (TLR1/2) agonist; induces production of TNF-α and IL-6 in macrophages. Stimulates phosphorylation of p100/p110 and p60 in granulocytic-differentiated HL-60 cells. Promotes differentiation of naive CD4+ T cells into Th17 cells.

Technical Data

Formula:
C81H156N10O13S
Sequence:
CSKKKK

(Modifications: Cys = S-[2,3-Bis(palmitoyloxy)-(2-RS)-propyl]-N-palmitoyl]-Cys

Solubility:
Soluble to 1 mg/ml in 50% Ethanol / water
Storage:
Store the unopened product at -20 to -70 °C. Use a manual defrost freezer and avoid repeated freeze-thaw cycles. Do not use past expiration date.
CAS No:
112208-00-1

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
Tocris products are intended for laboratory research use only, unless stated otherwise.

Product Datasheets

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Reviews for Pam3CSK4

Average Rating: 5 (Based on 2 Reviews)

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TLR 1/2 agonist
By Tahmineh Safaie on 01/22/2020
Species: Mouse

Raw-Blue Cell lines were treated with 125 ng/ml of PAM3CSK4 and the level of SEAP was measured. SEAP level correlates with NFkB activation


Good product!
By Anonymous on 04/24/2018
Species: Human

I use this product to activate TLR2


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