Catalog Number: 3554
Biological Activity
Cell-permeable peptide cleaved from protease-activated receptor 1 (PAR1) upon receptor activation. Attenuates endothelial cell migration and proliferation (IC50 ~ 20 μM), and induces cell cycle arrest. Promotes activation of caspase-3 and exhibits pro-apoptotic activity in vitro. Inhibits angiogenesis and exhibits cardioprotective activity in vivo.

Parstatin (human) also available.

Technical Data
  • M.Wt:
    4419.19
  • Formula:
    C189H326N58O57S3
  • Sequence:
    MGPRRLLIVALGLSLCGPLLSSRVPMSQPESERTDATVNPR
  • Solubility:
    Soluble to 1 mg/ml in water
  • Storage:
    Store at -20°C
  • CAS No:
    1065756-01-5
The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis. All Tocris products are intended for laboratory research use only.
Additional Information
Other Product-Specific Information:
Background References
  1. Parstatin, the cleaved peptide on proteinase-activated receptor 1 activation, is a potent inhibitor of activation.
    Zania et al.
    J.Pharmacol.Exp.Ther., 2009;328:378
  2. Parstatin: a cryptic peptide involved in cardioprotection after ischaemic and reperfusion injury.
    Strande et al.
    Cardiovasc.Res., 2009;83:325

Have you used Parstatin (mouse)?

Submit a review and receive a $25US/€18/£15/$25CAN amazon gift card if you include an image - $10US/€7/£6/$10CAN Amazon card for reviews without an image. Limited to verified customers in USA, Canada and Europe.

Tocris Bioscience is the leading supplier of novel and exclusive tools for life science research with over 30 years' experience in the industry. Tocris is a Bio-Techne brand.

Order Details

Note:

Contact Information

Calculators

Molarity Calculator

Calculate the mass, volume, or concentration required for a solution.
=
x
x
g/mol

*When preparing stock solutions always use the batch-specific molecular weight of the product found on the vial label and SDS / CoA (available online).

R&D Systems Guarantee

Feedback

Customer Information