PD 118057

Catalog # Availability Size / Price Qty
2830/10
2830/50

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PD 118057 | CAS No. 313674-97-4 | Voltage-gated Potassium Channel Activators
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Description: Selective KV11.1 (hERG) channel activator

Chemical Name: 2-[[4-[2-(3,4-Dichlorophenyl)ethyl]phenyl]amino]benzoic acid

Purity: ≥99%

Product Details
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Biological Activity

PD 118057 is a human ether-a-go-go (hERG) KV11.1 potassium channel activator. Displays no major effect on INa, ICa/L, IK1 and IKs currents. Causes resting membrane hyperpolarization and decreases action potential duration in rat myocytes in vitro.

Technical Data

M.Wt:
386.27
Formula:
C21H17Cl2NO2
Solubility:
Soluble to 100 mM in DMSO and to 20 mM in ethanol
Purity:
≥99%
Storage:
Store at -20°C
CAS No:
313674-97-4

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
Tocris products are intended for laboratory research use only, unless stated otherwise.

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