Human ether-a-go-go (hERG) KV
11.1 potassium channel activator. Displays no major effect on INa
currents. Causes resting membrane hyperpolarization and decreases action potential duration in rat myocytes in vitro
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Novel potent human ether-a-go-go-related gene (hERG) potassium channel enhancers and their in vitro antiarrhythmic activity.
Zhou et al.
Pharmacological and biophysical isolation of K+ currents encoded by ether-a-go-go-related genes in murine hepatic portal vein smooth muscle cells.
Yeung and Greenwood
hERG: The long and short of it.
Heart Rhythm, 2008;5:591