PD 118057

Catalog # Availability Size / Price Qty
2830/10
2830/50
Cat.No. 2830 - PD 118057 | C21H17Cl2NO2 | CAS No. 313674-97-4
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Description: Selective KV11.1 (hERG) channel activator

Chemical Name: 2-[[4-[2-(3,4-Dichlorophenyl)ethyl]phenyl]amino]benzoic acid

Purity: ≥99%

Product Details
Reviews (1)

Biological Activity

Human ether-a-go-go (hERG) KV11.1 potassium channel activator. Displays no major effect on INa, ICa/L, IK1 and IKs currents. Causes resting membrane hyperpolarization and decreases action potential duration in rat myocytes in vitro.

Technical Data

M.Wt:
386.27
Formula:
C21H17Cl2NO2
Solubility:
Soluble to 100 mM in DMSO and to 20 mM in ethanol
Purity:
≥99%
Storage:
Store at -20°C
CAS No:
313674-97-4

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
Tocris products are intended for laboratory research use only, unless stated otherwise.

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Amazing Kv channel activator
By Anonymous on 10/23/2018
Species: Human

Amazing Kv channel activator, shows high channel activation on almost all cell lines that express Kv channels. Performs great on experimental conditions, is stable and would buy again soon.


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