PD 173212

Key Product Details

Product Description

PD 173212 is a potent N-type voltage-gated calcium channel blocker (IC₅₀ = 36 nM). Displays selectivity over K⁺, Na⁺ and L-type Ca²⁺ channels. Prevents tonic seizures in the audiogenic seizure model in vivo.

Product Specifications for PD 173212

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.

Solubility

Preparing Stock Solutions for PD 173212

The following data is based on the product molecular weight 599.85.

Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which all affect the solvent volumes required to prepare stock solutions.

Select a batch to recalculate based on the batch molecular weight:

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Concentration / Solvent Volume / Mass	1 mg	5 mg	10 mg
1 mM	1.67 mL	8.34 mL	16.67 mL
5 mM	0.33 mL	1.67 mL	3.33 mL
10 mM	0.17 mL	0.83 mL	1.67 mL
50 mM	0.03 mL	0.17 mL	0.33 mL

Calculators

Background References

References are publications that support the biological activity of the product.

• Hu Structure-activity relationships of N-methyl-N-aralkyl-peptidylamines as novel N-type calcium channel blockers. Bioorg.Med.Chem.Letts.

Product Documents for PD 173212