PDD 00017272

Tocris Bioscience | Catalog # 7006

Potent PARG inhibitor
Tocris Bioscience

Key Product Details

Description

Potent PARG inhibitor
View all PARG Inhibitors »

Product Description

PDD 00017272 is a potent poly (ADP ribose) glycohydrolase (PARG) inhibitor (IC50 values are 4.8 nM in biochemical assay and 9.2 nM in cell based assay).

Licensing Information

Sold under license from Cancer Research Technology Ltd (Ximbio).

Product Specifications for PDD 00017272

Molecular Weight

531.66

Formula

C23H25N5O4S3

Storage

Store at -20°C

Purity

≥98% (HPLC)

Chemical Name

1-[(2,4-Dimethyl-5-thiazolyl)methyl]-1,2,3,4-tetrahydro-N-(1-methylcyclopropyl)-3-[(2-methyl-5-thiazolyl)methyl]-2,4-dioxo-6-quinazolinesulfonamide

CAS Number

1945950-20-8

PubChem ID

134169694

InChI Key

QOEXRJYTAZZRPL-UHFFFAOYSA-N

SMILES

CC1=NC=C(S1)CN2C(N(C3=CC=C(S(=O)(NC4(CC4)C)=O)C=C3C2=O)CC5=C(N=C(S5)C)C)=O

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.

Solubility

Solvent Max Conc. mg/mL Max Conc. mM
Solubility
DMSO 10.63 20 with gentle warming

Preparing Stock Solutions for PDD 00017272

The following data is based on the product molecular weight 531.66.

Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which all affect the solvent volumes required to prepare stock solutions.

Select a batch to recalculate based on the batch molecular weight:

Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
0.2 mM 9.40 mL 47.02 mL 94.05 mL
1 mM 1.88 mL 9.40 mL 18.81 mL
2 mM 0.94 mL 4.70 mL 9.40 mL
10 mM 0.19 mL 0.94 mL 1.88 mL

Calculators

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Background References

References are publications that support the biological activity of the product. See our Citations tab to view 8 publications citing the usage of this product.

Product Documents for PDD 00017272

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot or batch number in the search box below.

Product Specific Notices for PDD 00017272

For research use only

Related Research Areas

Infectious Diseases

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