Chemical Name: 1-[(2,4-Dimethyl-5-thiazolyl)methyl]-2,3-dihydro-N-methyl-N-(1-methylcyclopropyl)-2-oxo-3-(1,2,4-thiadiazol-5-yl)-1H-benzimidazole-5-sulfonamide
Biological ActivityPDD 00031705 is a negative control for PDD 00017238 (Cat. No. 7007).
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Tocris products are intended for laboratory research use only, unless stated otherwise.
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First-in-class chemical probes against poly(ADP-ribose) glycohydrolase (PARG) inhibit DNA repair with differential pharmacology to Olaparib.
James et al.
ACS Chem.Biol., 2016;11:3179
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