PDD 00017238

Tocris Bioscience | Catalog # 7007

High affinity and potent PARG inhibitor
Tocris Bioscience

Key Product Details

Description

High affinity and potent PARG inhibitor
View all PARG Inhibitors »

Product Description

PDD 00017238 is a high affinity and potent PARG inhibitor (Kd = 3.09 nM; IC50 = 40 nM).

Negative control PDD 00031705 (Cat. No. 7009) also available.

Licensing Information

Sold under license from Cancer Research Technology Ltd (Ximbio).

Product Specifications for PDD 00017238

Molecular Weight

476.59

Formula

C19H20N6O3S3

Storage

Store at -20°C

Purity

≥98% (HPLC)

Chemical Name

1-[(2,4-Dimethyl-5-thiazolyl)methyl]-2,3-dihydro-N-(1-methylcyclopropyl)-2-oxo-3-(1,2,4-thiadiazol-5-yl)-1H-benzimidazole-5-sulfonamide

CAS Number

1952247-05-0

PubChem ID

121415983

InChI Key

FLUZEVGWXJVSPX-UHFFFAOYSA-N

SMILES

CC1=NC(C)=C(S1)CN2C(N(C3=CC(S(=O)(NC4(CC4)C)=O)=CC=C23)C5=NC=NS5)=O

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.

Solubility

Solvent Max Conc. mg/mL Max Conc. mM
Solubility
DMSO 0.95 2

Preparing Stock Solutions for PDD 00017238

The following data is based on the product molecular weight 476.59.

Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which all affect the solvent volumes required to prepare stock solutions.

Select a batch to recalculate based on the batch molecular weight:

Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
0.02 mM 104.91 mL 524.56 mL 1,049.12 mL
0.1 mM 20.98 mL 104.91 mL 209.82 mL
0.2 mM 10.49 mL 52.46 mL 104.91 mL
1 mM 2.10 mL 10.49 mL 20.98 mL

Calculators

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Background References

References are publications that support the biological activity of the product. See our Citations tab to view 19 publications citing the usage of this product.

Product Documents for PDD 00017238

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot or batch number in the search box below.

Product Specific Notices for PDD 00017238

For research use only

Related Research Areas

Infectious Diseases

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