PEAQX tetrasodium salt

Key Product Details

Product Description

PEAQX tetrasodium salt is a potent NMDA receptor antagonist (IC₅₀ = 8 nM). Exhibits >100-fold selectivity for hGluN2A (formally hNR2A) containing receptors over hGluN2B (hNR2B). Anticonvulsant in vivo.

Please refer to IUPHAR Guide to Pharmacology for the most recent naming conventions.

Product Specifications for PEAQX tetrasodium salt

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.

Solubility

Preparing Stock Solutions for PEAQX tetrasodium salt

The following data is based on the product molecular weight 542.14.

Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which all affect the solvent volumes required to prepare stock solutions.

Select a batch to recalculate based on the batch molecular weight:

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Concentration / Solvent Volume / Mass	1 mg	5 mg	10 mg
0.1 mM	18.45 mL	92.23 mL	184.45 mL
0.5 mM	3.69 mL	18.45 mL	36.89 mL
1 mM	1.84 mL	9.22 mL	18.45 mL
5 mM	0.37 mL	1.84 mL	3.69 mL

Calculators

Background References

References are publications that support the biological activity of the product. See our Citations tab to view 4 publications citing the usage of this product.

• Auberson 5-Phosphonomethylquinoxalinediones as competitive NMDA receptor antagonists with a preference for the human 1A/2A, rather than 1A/2B receptor composition. Bioorg.Med.Chem.Lett. 2002 PMID: 11909726

Product Documents for PEAQX tetrasodium salt