Biological ActivityPEN (mouse) is a endogenous peptide GPR83 agonist. ProSAAS-derived neuropeptide. Activates phospholipase C (PLC)-mediated signaling cascade in mouse hypothalamus.
The technical data provided above is for guidance only.
For batch specific data refer to the Certificate of Analysis.
Tocris products are intended for laboratory research use only, unless stated otherwise.
Identification of GPR83 as the receptor for the neuroendocrine peptide PEN.
Gomes et al.
Neuropeptide PEN and its receptor GPR83: distribution, signaling, and regulation.
Mack et al.
ACS Chem.Neurosci., 2019;10:1884
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