Antimicrobial. Neuroprotective; inhibits constitutive nitric oxide synthase in the brain and acts as a NMDA glutamate receptor antagonist.
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Pentamidine is an N-methyl-D-aspartate receptor antagonist and is neuroprotective in vitro.
Reynolds and Aizeman
Inhibition of constitutive nitric oxide synthase in the brain by pentamidine, a calmodulin antagonist.
Kitamura et al.
The citations listed below are publications that use Tocris products. Selected citations for Pentamidine isethionate include:
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