Pentostatin

  ( 3 citations )    
Product Datasheet
Catalog Number:2033
Alternate Names:Deoxycoformycin
Chemical Name:(8R)-3-(2-Deoxy-β-D-erythro-pentofuranosyl)-3,4,7,8-tetrahydroimidazo[4,5-d][1,3]diazepin-8-ol
Product Details
Citations (3)
Reviews
Biological Activity
Irreversible inhibitor of adenosine deaminase (Ki = 2.5 pM). Anticancer agent.
Technical Data
  • M.Wt:
    268.27
  • Formula:
    C11H16N4O4
  • Solubility:
    Soluble to 100 mM in water and to 75 mM in DMSO
  • Purity:
    >99
  • Storage:
    Store at +4°C
  • CAS No:
    53910-25-1
The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis. All Tocris products are intended for laboratory research use only.
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Citations:

The citations listed below are publications that use Tocris products. Selected citations for Pentostatin include:

3 Citations: Showing 1 - 3
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  1. Erythrocytes retain hypoxic adenosine response for faster acclimatization upon re-ascent.
    Authors: Song
    Nat Commun  2017;8:14108
  2. Adenosine arrests breast cancer cell motility by A3 receptor stimulation.
    Authors: Ledderose Et al.
    Purinergic Signalling  2016;
  3. Inhibition of adenosine deaminase (ADA)-mediated metabolism of cordycepin by natural substances.
    Authors: Li Et al.
    PLoS Comput Biol  2015;3:e00121

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