Catalog Number: 2033
Alternate Names: Deoxycoformycin
Chemical Name: (8R)-3-(2-Deoxy-β-D-erythro-pentofuranosyl)-3,4,7,8-tetrahydroimidazo[4,5-d][1,3]diazepin-8-ol
Biological Activity
Irreversible inhibitor of adenosine deaminase (Ki = 2.5 pM). Anticancer agent.
Technical Data
  • M.Wt:
  • Formula:
  • Solubility:
    Soluble to 100 mM in water and to 75 mM in DMSO
  • Purity:
  • Storage:
    Store at +4°C
  • CAS No:
The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis. All Tocris products are intended for laboratory research use only.
Background References
  1. Pentostatin: future directions.
    Klohs and Kraker
    Pharmacol.Rev., 1992;44:459
  2. Purine nucleoside analogues and combination therapies in B-cell chronic lymphocytic leukemia: dawn of a new era.
    Nabhan et al.
    Leukemia Res., 2004;28:429

The citations listed below are publications that use Tocris products. Selected citations for Pentostatin include:

Showing Results 1 - 2 of 2

  1. Adenosine�arrests�breast�cancer�cell�motility�by�A3�receptor�stimulation.
    Authors: Ledderose Et al.
    Purinergic Signalling
  2. Inhibition of adenosine deaminase (ADA)-mediated metabolism of cordycepin by natural substances.
    Authors: Li Et al.
    PLoS Comput Biol
Tocris Bioscience is the leading supplier of novel and exclusive tools for life science research with over 30 years' experience in the industry. Tocris is a Bio-Techne brand.

Order Details


Contact Information

Molarity Calculator
Calculate the mass, volume or concentration required for a solution

The molarity calculator is based on the following equation:

Mass (g) = Concentration (mol/L) x Volume (L) x Molecular Weight (g/mol)
An example of a molarity calculation using the molarity calculator:
What is the mass of compound required to make a 10 mM stock solution in 10 ml of water given that the molecular weight of the compound is 197.13 g/mol?

R&D Systems Guarantee

or select another batch:


Customer Information