Pentostatin

Catalog # Availability Size / Price Qty
2033/10
2033/50
Pentostatin | CAS No. 53910-25-1 | Deaminase Inhibitors
1 Image
Description: Adenosine deaminase inhibitor
Alternative Names: Deoxycoformycin

Chemical Name: (8R)-3-(2-Deoxy-β-D-erythro-pentofuranosyl)-3,4,7,8-tetrahydroimidazo[4,5-d][1,3]diazepin-8-ol

Purity: ≥99%

Product Details
Citations (3)
Reviews

Biological Activity

Irreversible inhibitor of adenosine deaminase (Ki = 2.5 pM). Anticancer agent.

Technical Data

M.Wt:
268.27
Formula:
C11H16N4O4
Solubility:
Soluble to 100 mM in water and to 75 mM in DMSO
Purity:
≥99%
Storage:
Store at +4°C
CAS No:
53910-25-1

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
Tocris products are intended for laboratory research use only, unless stated otherwise.

Background References

  1. Pentostatin: future directions.
    Klohs and Kraker
    Pharmacol.Rev., 1992;44:459
  2. Purine nucleoside analogues and combination therapies in B-cell chronic lymphocytic leukemia: dawn of a new era.
    Nabhan et al.
    Leukemia Res., 2004;28:429

Product Datasheets

or select another batch:
Reconstitution Calculator
Molarity Calculator

Reconstitution Calculator

The reconstitution calculator allows you to quickly calculate the volume of a reagent to reconstitute your vial. Simply enter the mass of reagent and the target concentration and the calculator will determine the rest.

=
÷

Molarity Calculator

=
x
x
g/mol

*When preparing stock solutions always use the batch-specific molecular weight of the product found on the vial label and SDS / CoA (available online).

⚠ WARNING: This product can expose you to chemicals including Pentostatin, which is known to the State of California to cause reproductive toxicity with developmental effects. For more information, go to www.P65Warnings.ca.gov

Citations for Pentostatin

The citations listed below are publications that use Tocris products. Selected citations for Pentostatin include:

3 Citations: Showing 1 - 3

FAQs

No product specific FAQs exist for this product, however you may

View all Small Molecule FAQs

Reviews for Pentostatin

There are currently no reviews for this product. Be the first to review Pentostatin and earn rewards!

Have you used Pentostatin?

Submit a review and receive an Amazon gift card.

$25/€18/£15/$25CAN/¥75 Yuan/¥1250 Yen for a review with an image

$10/€7/£6/$10 CAD/¥70 Yuan/¥1110 Yen for a review without an image

Submit a Review
Tocris Bioscience is the leading supplier of novel and exclusive tools for life science research with over 30 years' experience in the industry. Tocris is a Bio-Techne brand.