Key Product Details

Species Reactivity

Mouse

Applications

Western Blot

Label

DyLight 755 (Excitation = 754 nm, Emission = 776 nm)

Antibody Source

Monoclonal Rat IgG2A Clone # 300103
View all Pentraxin 2/SAP Primary Antibodies »

Product Specifications

Immunogen

Mouse myeloma cell line NS0-derived recombinant mouse Pentraxin 2/SAP
Gln21-Asp224
Accession # P12246

Specificity

Detects mouse Pentraxin 2/SAP in direct ELISAs and Western blots. In direct ELISAs and Western blots, 100% cross‑reactivity with recombinant rat Pentraxin 2/SAP is observed. In Western blots, 100% cross-reactivity with recombinant human (rh) Pentraxin 2/SAP is observed, but no cross-reactivity with rhPentraxin 2/SAP in direct ELISAs is observed.

Clonality

Monoclonal

Host

Rat

Isotype

IgG2A

Applications for Pentraxin 2/SAP Antibody (300103) [DyLight 755]

Application
Recommended Usage

Western Blot

Optimal dilutions of this antibody should be experimentally determined.
Application Notes
Optimal dilution of this antibody should be experimentally determined.

Formulation, Preparation, and Storage

Purification

Protein A or G purified from hybridoma culture supernatant

Formulation

50mM Sodium Borate

Preservative

0.05% Sodium Azide

Concentration

Please see the vial label for concentration. If unlisted please contact technical services.

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store at 4C in the dark.

Background: Pentraxin 2/SAP

Serum Amyloid P (SAP) is a non-fibrillar plasma glycoprotein that belongs to the pentraxin family. It is universally found in amyloid deposits and this is probably due to its specific calcium-dependent binding to motifs present on all types of amyloid fibrils. SAP is also found to prevent fibrillar breakdown by enzymes and it is believed that it helps maintains stability of the amyloid deposits (1,2). It has been shown that SAP binds monocytes with high avidity, but does not bind to erythrocytes, NK cells, T lymphocytes or B lymphocytes (3). SAP production can be induced by exposure to IL-1, IL-6 and IFN-beta. The SAP-inducing activity was neutralized by antibodies to each of the recombinant cytokines (4).

Long Name

Serum Amyloid P Component

Alternate Names

APCS, PTX2, SAP

Gene Symbol

APCS

Additional Pentraxin 2/SAP Products

Product Documents for Pentraxin 2/SAP Antibody (300103) [DyLight 755]

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot or batch number in the search box below.

Download SDS

Product Specific Notices for Pentraxin 2/SAP Antibody (300103) [DyLight 755]



DyLight (R) is a trademark of Thermo Fisher Scientific Inc. and its subsidiaries.

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

Customer Reviews for Pentraxin 2/SAP Antibody (300103) [DyLight 755]

There are currently no reviews for this product. Be the first to review Pentraxin 2/SAP Antibody (300103) [DyLight 755] and earn rewards!

Have you used Pentraxin 2/SAP Antibody (300103) [DyLight 755]?

Submit a review and receive an Amazon gift card!

$25/€18/£15/$25CAN/¥2500 Yen for a review with an image

$10/€7/£6/$10CAN/¥1110 Yen for a review without an image

Submit a review
Amazon Gift Card

FAQs

No product specific FAQs exist for this product.

View all FAQs for Antibodies